ReviewEpigenetics2012
Trans-chromosomal methylation.
Review in Epigenetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Transcriptome and DNA methylation analyses provide insight into the heterosis of growth-related traits in hybrid yellow croaker.BMC genomics · 2025Article
- Small RNA-mediated DNA methylation during plant reproduction.The Plant cell · 2023Review
- Will epigenetics be a key player in crop breeding?Frontiers in plant science · 2022Review
- Embryo CHH hypermethylation is mediated by RdDM and is autonomously directed in Brassica rapa.Genome biology · 2021Article
- Natural epialleles of Arabidopsis SUPERMAN display superwoman phenotypes.Communications biology · 2020Article
- InPlants (Basel, Switzerland) · 2020Article
- Transposon-associated epigenetic silencing during Pleurotus ostreatus life cycle.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- Epigenetic regulation of agronomical traits in Brassicaceae.Plant cell reports · 2018Review
- Twenty-four-nucleotide siRNAs produce heritable trans-chromosomal methylation in F1 Arabidopsis hybrids.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Methylation interactions in Arabidopsis hybrids require RNA-directed DNA methylation and are influenced by genetic variation.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Heritable DNA Methylation in CD4+ Cells among Complex Families Displays Genetic and Non-Genetic Effects.PloS one · 2016Article
- Arabidopsis MSH1 mutation alters the epigenome and produces heritable changes in plant growth.Nature communications · 2015Article
- Intraspecific Arabidopsis hybrids show different patterns of heterosis despite the close relatedness of the parental genomes.Plant physiology · 2014Article
- Inheritance of Trans Chromosomal Methylation patterns from Arabidopsis F1 hybrids.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Article
- Epiallelic variation in Arabidopsis thaliana.Cold Spring Harbor symposia on quantitative biology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The epigenome plays a vital role in helping to maintain and regulate cell functions in all organisms. Alleles with differing epigenetic marks in the same nucleus do not function in isolation but can interact in trans to modify the epigenetic state of one or both alleles. This is particularly evident when two divergent epigenomes come together in a hybrid resulting in thousands of alterations to the methylome. These changes mainly involve the methylation patterns at one allele being changed to resemble the methylation patterns of the other allele, in processes we have termed trans-chromosomal methylation (TCM) and trans-chromosomal demethylation (TCdM). These processes are primarily modulated by siRNAs and the RNA directed DNA methylation pathway. Drawing from other examples of trans-allelic interactions, we describe the process of TCM and TCdM and the effect such changes can have on genome activity. Trans-allelic epigenetic interactions may be a common occurrence in many biological systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.