Evidence map›Paper›PMID 22705336›Full record

ArticleEnvironmental research2012

Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation.

Michelle L Bell, Kathleen Belanger, Keita Ebisu, Janneane F Gent, Brian P Leaderer

Open access · greenAbstract readComparative Study
In one paragraph

Article in Environmental research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trimester-specific exposure to PMBMC pregnancy and childbirth · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Trimester effects of source-specific PMEnvironmental health : a global access science source · 2021
    Article
  8. Chemical Characterization of Seasonal PMInternational journal of environmental research and public health · 2020
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. The Association between Airborne PMEnvironmental research letters : ERL [Web site] · 2014
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michelle L BellYale University, School of Forestry and Environmental Studies, 195 Prospect St., New Haven, CT 06511, USA. michelle.bell@yale.edu
Kathleen Belanger
Keita Ebisu
Janneane F Gent
Brian P Leaderer
Yale University · US

Funding

Effect of Air Pollution and Traffic on Birth OutcomesR01ES016317 · NIEHS · YALE UNIVERSITY · PI BELANGER, KATHLEEN, BELL, MICHELLE L · 2008 to 2012
$2.9M
Effects of Fine Particle Composition on Birth OutcomesR01ES019587 · NIEHS · YALE UNIVERSITY · PI BELL, MICHELLE L · 2011 to 2015
$2.6M
Statistical Methods for Complex Enivronmental Health DataR01ES019560 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI PENG, ROGER · 2011 to 2015
$1.8M
National Assessment of the Mortality and Morbidity Effects of Tropospheric OzoneR01ES015028 · NIEHS · YALE UNIVERSITY · PI BELL, MICHELLE L · 2006 to 2010
$477k
NIEHS NIH HHS R01 ES015028NIEHS NIH HHS R01ES015028NIEHS NIH HHS R01 ES016317NIEHS NIH HHS R01ES016317NIEHS NIH HHS R01 ES019560NIEHS NIH HHS R01ES019560NIEHS NIH HHS R01 ES019587NIEHS NIH HHS R01ES019587
6 · The paper itself

Abstract

Airborne particles are linked to numerous health impacts, including adverse pregnancy outcomes. Most studies of particles examined total mass, although the chemical structure of particles varies widely. We investigated whether mother's exposure to potassium (K) and titanium (Ti) components of airborne fine particulate matter (PM(2.5)) during pregnancy was associated with birth weight or risk of low birth weight (<2500 g) for term infants. The study population was 76,788 infants born in four counties in Connecticut and Massachusetts, US, for August 2000-February 2004. Both K and Ti were associated with birth weight. An interquartile range (IQR) increase K was associated with an 8.75% (95% confidence interval (CI): 1.24-16.8%) increase in risk of low birth weight. An IQR increase in Ti was associated with a 12.1% (95% CI: 3.55-21.4%) increase in risk of low birth weight, with an estimate of 6.41% (95% CI: -5.80-20.2%) for males and 16.4% (95% CI: 5.13-28.9%) for females. Results were robust to sensitivity analysis of first births only, but not adjustment by co-pollutants. Disentangling the effects of various chemical components is challenging because of the covariance among some components due to similar sources. Central effect estimates for infants of African-American mothers were higher than those of white mothers, although the confidence intervals overlapped. Our results indicate that exposure to airborne potassium and titanium during pregnancy is associated with lower birth weight. Associations may relate to chemical components of sources producing K and Ti.

Indexed as

AdultAir PollutantsBirth WeightBlack or African AmericanConnecticutFemaleHumansInfant, NewbornLinear ModelsMaleMassachusettsParticulate MatterPotassiumPregnancyPrenatal Exposure Delayed EffectsRisk AssessmentAir PollutantsParticulate MatterPotassiumTitanium

Identifiers

PMID22705336
PMCPMC3418490
OpenAlexW2076319009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.