ArticleImmunity2012
A closer look at TCR germline recognition.
Article in Immunity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Biophysical and Structural Features of αβT-Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T-Cell Activation.Immunological reviews · 2025Review
- The Evolving T Cell Receptor Recognition Code: The Rules Are More Like Guidelines.Immunological reviews · 2025Review
- Updates on ankylosing spondylitis: pathogenesis and therapeutic agents.Journal of rheumatic diseases · 2023Review
- A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry.Nature communications · 2022Article
- Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better.Journal for immunotherapy of cancer · 2022Article
- Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response.Frontiers in immunology · 2022Article
- Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation.Cell reports · 2021Article
- An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.Biochemistry · 2020Article
- TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis.EBioMedicine · 2019Article
- Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer.Nature communications · 2018Article
- The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics.Seminars in cell & developmental biology · 2018Review
- NMR-directed design of pre-TCRβ and pMHC molecules implies a distinct geometry for pre-TCR relative to αβTCR recognition of pMHC.The Journal of biological chemistry · 2018Article
- A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions.JCI insight · 2017Article
- Genetic variation in MHC proteins is associated with T cell receptor expression biases.Nature genetics · 2016Article
- The immunological synapse.Cancer immunology research · 2014Review
- The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function.Nature immunology · 2014Review
- A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- Diversity of γδ T-cell antigens.Cellular & molecular immunology · 2013Review
- T cells and their eons-old obsession with MHC.Immunological reviews · 2012Review
- Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
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Authors and funding
7 authors.
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Abstract
PubMed holds no abstract for this paper.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.