Evidence map›Paper›PMID 22704171›Full record

ArticleBMC research notes2012

DSCR9 gene simultaneous expression in placental, testicular and renal tissues from baboon (Papio hamadryas).

Irám Pablo Rodriguez-Sanchez, María Lourdes Garza-Rodríguez, María Elizabeth Tejero, Shelley A Cole, Anthony G Comuzzie, Hugo Alberto Barrera-Saldaña

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Irám Pablo Rodriguez-SanchezVitaxentrum, Blvd, Puerta del Sol 1005, Colinas de San Jerónimo, Monterrey, Nuevo León, 64460, Mexico.
María Lourdes Garza-Rodríguez
María Elizabeth Tejero
Shelley A Cole
Anthony G Comuzzie
Hugo Alberto Barrera-Saldaña
Universidad Autónoma de Nuevo León · MXTexas Biomedical Research Institute · USDiagnostics Research Group · US

Funding

WNV REPLIVAX VACCINE IN NON-HUMAN PRIMATESP51RR013986 · NCRR · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI GAUDUIN, MARIE-CLAIRE ELISABETH · 1999 to 2011
$79.1M
VETERINARY SERVICES--COREP01HL028972 · NHLBI · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI RICE, KAREN S · 1985 to 2012
$42.0M
EXTRAMULAR RESEARCH FACILITIES CONSTRUCTIONC06RR017515 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 2003 to 2003
$3.1M
EXTRAMURAL RES FACILITIES CONSTRC06RR015456 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 2001 to 2001
$1.1M
MOLECULAR AND BIOCHEMICAL GENETICS LABORATORY RENOVATIONC06RR013556 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 1998 to 1998
–
BABOON F-CAGE FACILITY FOR PRIMATE RESEARCH CENTERC06RR014578 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 1999 to 1999
–
NCRR NIH HHS C06RR014578NCRR NIH HHS C06RR015456NCRR NIH HHS C06 RR017515NCRR NIH HHS C06 RR13556NCRR NIH HHS P51 RR013986NCRR NIH HHS P51RR013986NHLBI NIH HHS P01 HL028972
6 · The paper itself

Abstract

backgroundIn 2002 Takamatsu and co-workers described the human DSCR9 gene and observed that it was transcriptionally active in human testicular tissue, but no protein was identified as a product of this transcript. Similar results were obtained in chimpanzee tissue. This gene has not been detected in species other than primates, suggesting that DSCR9 is exclusively found in these mammals.

resultsWe report evidence of DSCR9 expression in placenta, testis and kidney of baboon (Papio hamadryas). We used primers specific for DSCR9 to amplify transcripts through reverse transcription (RT) coupled to polymerase chain reaction (PCR). Furthermore, PCR was used to amplify the complete DSCR9 gene from genomic DNA from three baboons. We amplified and sequenced five overlapping segments that were assembled into the 3284 bp baboon DSCR9 gene, including the putative promoter and the entire transcriptional unit (5'-UTR, CDS and 3'-UTR).

conclusionsThe baboon DSCR9 gene is highly similar to the human counterpart. The isolated transcripts from baboon tissues (placenta, testis and kidney) of three different baboons correspond to the human orthologous gene.

Indexed as

Gene Expression RegulationAmino Acid SequenceAnimalsBase SequenceDatabases, Nucleic AcidFemaleHumansKidneyMaleMembrane ProteinsMolecular Sequence DataPapio hamadryasPlacentaPregnancyPromoter Regions, GeneticRNA, MessengerMembrane ProteinsRNA, Messenger

Identifiers

PMID22704171
PMCPMC3410801
OpenAlexW2156043792

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.