Evidence map›Paper›PMID 22703916›Full record

ArticleJournal of the American Academy of Dermatology2012

The dysplastic nevus: from historical perspective to management in the modern era: part II. Molecular aspects and clinical management.

Keith Duffy, Douglas Grossman

Abstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Targeting the ERK Signaling Pathway in Melanoma.International journal of molecular sciences · 2019
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. [Dysplastic melanocytic nevus].Der Pathologe · 2015
    Review
  11. Article
  12. Article
  13. The so-called dysplastic nevus is not dysplastic at all.Dermatology practical & conceptual · 2013
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Keith DuffyDepartment of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Douglas Grossman

Funding

Personalized melanoma chemopreventionR01CA166710 · NCI · UNIVERSITY OF UTAH · PI CASSIDY, PAMELA B., GROSSMAN, DOUGLAS · 2012 to 2016
$1.6M
NCI NIH HHS R01 CA166710
6 · The paper itself

Abstract

The dysplastic nevus is a discreet histologic entity that exhibits some clinical and histologic features overlapping with common nevi and melanoma. These overlapping features present a therapeutic challenge, and with a lack of accepted guidelines, the management of dysplastic nevi remains a controversial subject. Although some differences between dysplastic and common nevi can be detected at the molecular level, there are currently no established markers to predict biologic behavior. In part II of this continuing medical education article, we will review the molecular aspects of dysplastic nevi and their therapeutic implications. Our goal is to provide the clinician with an up-to-date understanding of this entity to facilitate clinical management of patients with nevi that have histologic dysplasia.

Indexed as

ApoptosisCell ProliferationDysplastic Nevus SyndromeGenes, Tumor SuppressorHumansMicrosatellite InstabilityMutation

Identifiers

PMID22703916
PMCPMC3621132

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.