Evidence map›Paper›PMID 22702533›Full record

ArticleAllergy2012

International consensus on (ICON) pediatric asthma.

N G Papadopoulos, H Arakawa, K-H Carlsen, A Custovic, J Gern, R Lemanske, P Le Souef, M Mäkelä, G Roberts, G Wong and 58 more

Registry-linked trialAbstract readConsensus Statement
In one paragraph

Article in Allergy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02571660 (Efficacy of Vitamin D on the Clinical Management of Pediatric Patients With Asthma in the Hospital General Naval de Alta Especialidad), which is not on this map. Cited by 143 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02571660 phase3unknown statusnot on this mapstarted 2015, after this paper: background citation

Efficacy of Vitamin D on the Clinical Management of Pediatric Patients With Asthma in the Hospital General Naval de Alta Especialidad

TypeinterventionalSponsorHospital General Naval de Alta Especialidad - Escuela Medico NavalRan2015 to 2017Enrolled100ConditionsAsthmaArmsGINA treatment fot asthma +vit.D low supplementation dose, GINA treatment fot asthma +vit.D high supplementation dose
3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Non-invasive positive pressure ventilation for acute asthma in children.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Management of asthma exacerbations in the paediatric population: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Change in FEVChest · 2019
    Pooled it
  6. Leukotriene receptor antagonists for eczema.The Cochrane database of systematic reviews · 2018
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. The efficacy and safety of fluticasone/salmeterol compared to fluticasone in children younger than four years of age.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2019
    Trial
  12. Trial
  13. Trial
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

68 authors.

N G PapadopoulosDepartment of Allergy, 2nd Pediatric Clinic, University of Athens, Athens, Greece. gp@allergy.gr
H Arakawa
K-H Carlsen
A Custovic
J Gern
R Lemanske
P Le Souef
M Mäkelä
G Roberts
G Wong
H Zar
C A Akdis
L B Bacharier
E Baraldi
H P van Bever
J de Blic
A Boner
W Burks
T B Casale
J A Castro-Rodriguez
Y Z Chen
Y M El-Gamal
M L Everard
T Frischer
M Geller
J Gereda
D Y Goh
T W Guilbert
G Hedlin
P W Heymann
S J Hong
E M Hossny
J L Huang
D J Jackson
J C de Jongste
O Kalayci
N Aït-Khaled
S Kling
P Kuna
S Lau
D K Ledford
S I Lee
A H Liu
R F Lockey
K Lødrup-Carlsen
J Lötvall
A Morikawa
A Nieto
H Paramesh
R Pawankar
P Pohunek
J Pongracic
D Price
C Robertson
N Rosario
L J Rossenwasser
P D Sly
R Stein
S Stick
S Szefler
L M Taussig
E Valovirta
P Vichyanond
D Wallace
E Weinberg
G Wennergren
J Wildhaber
R S Zeiger

Funding

Virus-Bacterial Interactions and Exacerba of AsthmaP01HL070831 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E. · 2002 to 2017
$31.3M
RV-Mediated Mechanisms of Neutrophil Motility /InflammatU19AI070503 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E. · 2006 to 2010
$6.8M
Inner-City Asthma Consortium-266025496-266025496N01AI025496 · NIAID · UNIVERSITY OF WISCONSIN · PI BUSSE, WILLIAM · 2002 to 2006
–
NHLBI NIH HHS P01 HL070831NIAID NIH HHS N01 AI025496NIAID NIH HHS U19 AI070503
6 · The paper itself

Abstract

Asthma is the most common chronic lower respiratory disease in childhood throughout the world. Several guidelines and/or consensus documents are available to support medical decisions on pediatric asthma. Although there is no doubt that the use of common systematic approaches for management can considerably improve outcomes, dissemination and implementation of these are still major challenges. Consequently, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), recently formed by the EAACI, AAAAI, ACAAI, and WAO, has decided to propose an International Consensus on (ICON) Pediatric Asthma. The purpose of this document is to highlight the key messages that are common to many of the existing guidelines, while critically reviewing and commenting on any differences, thus providing a concise reference. The principles of pediatric asthma management are generally accepted. Overall, the treatment goal is disease control. To achieve this, patients and their parents should be educated to optimally manage the disease, in collaboration with healthcare professionals. Identification and avoidance of triggers is also of significant importance. Assessment and monitoring should be performed regularly to re-evaluate and fine-tune treatment. Pharmacotherapy is the cornerstone of treatment. The optimal use of medication can, in most cases, help patients control symptoms and reduce the risk for future morbidity. The management of exacerbations is a major consideration, independent of chronic treatment. There is a trend toward considering phenotype-specific treatment choices; however, this goal has not yet been achieved.

Indexed as

AdolescentAsthmaChildChild, PreschoolHumansInfantInfant, Newborn

Identifiers

PMID22702533
PMCPMC4442800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.