Evidence map›Paper›PMID 22702464›Full record

ArticleJournal of the American Geriatrics Society2012

Ethnic disparities in adherence to antihypertensive medications of medicare part D beneficiaries.

Holly M Holmes, Ruili Luo, Joseph T Hanlon, Linda S Elting, Maria Suarez-Almazor, James S Goodwin

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  16. Heart 2 Heart: Pilot Study of a Church-Based Community Health Worker Intervention for African Americans with Hypertension.Prevention science : the official journal of the Society for Prevention Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Holly M HolmesDepartment of General Internal Medicine, UT MD Anderson Cancer Center, Houston, Texas 77030, USA. hholmes@mdanderson.org
Ruili Luo
Joseph T Hanlon
Linda S Elting
Maria Suarez-Almazor
James S Goodwin

Funding

WOMENS HEALTH ACROSS THE NATION--COORDINATING CENTERU01AG012553 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKS, MARIA MORI · 1994 to 2019
$37.7M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Intervention to Reduce Dietary Sodium in HemodialysisR01NR010135 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SEVICK, MARY A · 2008 to 2011
$2.3M
Enhancing the Detection and Management of Adverse Drug Events in the Nursing HomeR01HS018721 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANDLER, STEVEN MARK · 2010 to 2013
$2.0M
Outcomes Research in Rheumatic Diseases: A Mentoring ProgramK24AR053593 · NIAMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SUAREZ-ALMAZOR, MARIA E · 2006 to 2015
$2.0M
The University of Pittsburgh's Comparative Effectiveness Research Scholars PrograK12HS019461 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPOOR, WISHWA N · 2010 to 2010
$1.9M
Established Investigator Award in Cancer Prevention & ControlK05CA134923 · NCI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GOODWIN, MD, JAMES S. · 2008 to 2019
$1.0M
Longitudinal Impact of CNS Polypharmacy on Geriatric SyndromesR01AG027017 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2006 to 2012
$801k
Medication Adherence Among Older Persons Enrolled in Medicare Part DK23AG038476 · NIA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOLMES, HOLLY M. · 2011 to 2015
$653k
Impact of Medicare Part D on Racial Disparities in Diabetes Treatment and OutcomeR01HS017695 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONOHUE, JULIE MARIE · 2009 to 2011
$628k
UPITT Program for Pharmaceutical Outcomes Research in AgingK07AG033174 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANLON, JOSEPH T · 2009 to 2013
$461k
AHRQ HHS K12 HS019461AHRQ HHS R01 HS017695AHRQ HHS R01 HS018721AHRQ HHS R01HS018721NCI NIH HHS K05 CA134923NIAMS NIH HHS K24 AR053593NIAMS NIH HHS K24AR053593NIA NIH HHS 3U01 AG012553NIA NIH HHS K07 AG033174NIA NIH HHS K07AG033174NIA NIH HHS K23 AG038476NIA NIH HHS K23AG038476NIA NIH HHS P30 AG024827NIA NIH HHS P30AG024827NIA NIH HHS R01 AG027017NIA NIH HHS R01 AG034056NIA NIH HHS R01AG034056NIA NIH HHS R56AG0207017NIA NIH HHS R56 AG027017NIA NIH HHS T32 AG021885NIA NIH HHS U01 AG012553NIMH NIH HHS R34 MH082682NINR NIH HHS R01 NR010135
6 · The paper itself

Abstract

objectivesTo determine the level of adherence to medications and characteristics of Part D beneficiaries associated with higher levels of antihypertensive medication adherence.

designRetrospective cohort study.

settingMedicare claims and Part D event files.

participantsMedicare Part D enrollees with prevalent uncomplicated hypertension who filled at least one antihypertensive prescription in 2006 and two prescriptions in 2007. MEASUREMENTS: Medication adherence was defined as an average medication possession ratio of 80% or greater. Potential factors associated with adherence evaluated were age, sex, race or ethnicity, socioeconomic factors, comorbidity, medication use, copayments, being in the coverage gap, and number of unique prescribers.

resultsOverall adherence was 79.5% of 168,522 Medicare Part D enrollees with prevalent uncomplicated hypertension receiving antihypertensive medicines in 2007. In univariate analysis, adherence varied significantly according to most patient factors. In multivariable analysis, lower odds of adherence persisted for blacks (odds ratio (OR) = 0.53, 95% confidence interval (CI) = 0.51-0.55), Hispanics (OR = 0.58, 95% CI = 0.55-0.61), and other non-white races (OR = 0.80 95% CI = 0.75-0.85) than for whites. Greater comorbidity and concurrent medication use were also associated with poorer adherence. Adherence was significantly different across several geographic regions.

conclusionA number of associations were identified between patient factors and adherence to antihypertensive drugs, with significant differences in adherence according to ethnicity. Improving adherence could have significant public health implications and could improve outcomes specific to hypertension, as well as improving cost and healthcare utilization.

Indexed as

Medicare Part DAgedAged, 80 and overAntihypertensive AgentsComorbidityFemaleHumansHypertensionLogistic ModelsMaleMedication AdherenceRetrospective StudiesUnited StatesAntihypertensive Agents

Identifiers

PMID22702464
PMCPMC3396714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.