ArticlePloS one2012
Dissociated representations of pleasant and unpleasant olfacto-trigeminal mixtures: an FMRI study.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Human olfactory sensitivity varies across geographical locations.Scientific reports · 2026Article
- Perceptual differences in olfactory fat discrimination are not detected in neural activation.Chemical senses · 2025Article
- Quantifying Peripheral Modulation of Olfaction by Trigeminal Agonists.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Local Brain Network Alterations and Olfactory Impairment in Alzheimer's Disease: An fMRI and Graph-Based Study.Brain sciences · 2023Article
- Pleasant and unpleasant odor identification ability is associated with distinct dimensions of negative symptoms transdiagnostically in psychotic disorders.Schizophrenia research · 2022Article
- Brain activation after nasal histamine provocation in house dust mite allergic rhinitis patients.Allergy · 2021Article
- Insula and Olfaction: A Literature Review and Case Report.Brain sciences · 2021Article
- Some like it, some do not: behavioral responses and central processing of olfactory-trigeminal mixture perception.Brain structure & function · 2021Article
- A network model of affective odor perception.PloS one · 2020Article
- Multisensory integration processing during olfactory-visual stimulation-An fMRI graph theoretical network analysis.Human brain mapping · 2018Article
- Food-Related Odors Activate Dopaminergic Brain Areas.Frontiers in human neuroscience · 2017Article
- From Nose to Brain: Un-Sensed Electrical Currents Applied in the Nose Alter Activity in Deep Brain Structures.Cerebral cortex (New York, N.Y. : 1991) · 2016Article
- The effect of verbal context on olfactory neural responses.Human brain mapping · 2014Article
- Olfactory tubercle stimulation alters odor preference behavior and recruits forebrain reward and motivational centers.Frontiers in behavioral neuroscience · 2014Article
- A pleasant familiar odor influences perceived stress and peripheral nervous system activity during normal aging.Frontiers in psychology · 2014Article
- Hedonic appreciation and verbal description of pleasant and unpleasant odors in untrained, trainee cooks, flavorists, and perfumers.Frontiers in psychology · 2014Article
- Repeated exposure to odors induces affective habituation of perception and sniffing.Frontiers in behavioral neuroscience · 2014Article
- Encoding and representation of intranasal CO2 in the mouse olfactory cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- The brain's specialized systems for aesthetic and perceptual judgment.The European journal of neuroscience · 2013Article
- Cross-modal integration of emotions in the chemical senses.Frontiers in human neuroscience · 2013Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How the pleasantness of chemosensory stimuli such as odorants or intranasal trigeminal compounds is processed in the human brain has been the focus of considerable recent interest. Yet, so far, only the unimodal form of this hedonic processing has been explored, and not its bimodal form during crossmodal integration of olfactory and trigeminal stimuli. The main purpose of the present study was to investigate this question. To this end, functional magnetic resonance imaging (fMRI) was used in an experiment comparing brain activation related to a pleasant and a relatively unpleasant olfacto-trigeminal mixture, and to their individual components (CO(2) alone, Orange alone, Rose alone). Results revealed first common neural activity patterns in response to both mixtures in a number of regions: notably the superior temporal gyrus and the caudate nucleus. Common activations were also observed in the insula, although the pleasant mixture activated the right insula whereas the unpleasant mixture activated the left insula. However, specific activations were observed in anterior cingulate gyrus and the ventral tegmental area only during the perception of the pleasant mixture. These findings emphasized for the firs time the involvement of the latter structures in processing of pleasantness during crossmodal integration of chemosensory stimuli.
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