Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2012
A combination appliance for obstructive sleep apnea: the effectiveness of mandibular advancement and tongue retention.
Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Different Oral Appliance Designs Demonstrate Different Rates of Efficacy for the Treatment of Obstructive Sleep Apnea: A Review Article.Bioengineering (Basel, Switzerland) · 2025Review
- A mandibular advancement device associated with lingual control: a new treatment option for obstructive sleep apnea?Sleep & breathing = Schlaf & Atmung · 2024Article
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Oral Appliances in Obstructive Sleep Apnea.Healthcare (Basel, Switzerland) · 2019Review
- Oral Appliance Treatment Response and Polysomnographic Phenotypes of Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015Article
- Management of severe sleep apnea secondary to juvenile arthritis with temporomandibular joint replacement and mandibular advancement.Journal of pharmacy & bioallied sciences · 2015Article
- Oral appliance treatment for obstructive sleep apnea: an update.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2014Review
- Innovative treatments for adults with obstructive sleep apnea.Nature and science of sleep · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThe purpose of this study was to determine if subjects with moderate-to-severe obstructive sleep apnea would experience increasing treatment effect when a tongue retention component was added to a mandibular repositioning appliance.
designCohort study.
settingSleep clinic. PATIENTS: Forty-four sequentially recruited patients with moderate-to-severe obstructive sleep apnea.
interventionsSubjects were sleep tested at 4 treatment stages of oral appliance therapy. The 4 stages were: 6-mm mandibular protrusion, 8-mm protrusion, 6-mm protrusion with a tongue retention bulb, and 8-mm protrusion with a tongue retention bulb. MEASUREMENTS AND
resultsForty-one of 44 subjects completed the protocol. There was a decrease in mean respiratory disturbance index from 33.5 events/h at baseline to 18.1 events/h at stage 4 (p = 0.001). Mean Epworth Sleepiness Scale (ESS) decreased from 12.3 at baseline to 9.0 at stage 4 (p = 0.0001.
conclusionsA combined approach utilizing both mandibular protrusion and tongue retention can provide effective treatment for moderate-to-severe obstructive sleep apnea. The addition of a tongue bulb may provide further treatment effect when mandibular protrusion is limited. Appliance designs that allow for convenient combination therapy need to be developed for this purpose.
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Registered trials
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