ArticleCardiology research and practice2012
Exercise and the cardiovascular system.
Article in Cardiology research and practice, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Mechanisms Involved in Exercise-Induced Cardioprotection: A Systematic Review.Arquivos brasileiros de cardiologia · 2015Pooled it
- Physical Activity Guidelines for Astronauts: An Immunological Perspective.Biomolecules · 2025Review
- The feasibility and effect of a peer-facilitated, remote handcycling sport program for aging adults with spinal cord injury or disease: a mixed methods case series.Spinal cord series and cases · 2025Article
- Impact of Long COVID-19 on Health Outcomes Among Adults With Preexisting Cardiovascular Disease and Hypertension: A Systematic Review.CJC open · 2024Review
- Cardiovascular Disease and Exercise: From Molecular Mechanisms to Clinical Applications.Journal of clinical medicine · 2022Review
- Amyloid Beta in Aging and Alzheimer's Disease.International journal of molecular sciences · 2022Review
- Assessment of Trimetazidine Treatment in Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention.Cardiology research and practice · 2022Article
- Cardiorespiratory Fitness and Atherosclerotic Cardiovascular Outcomes by Levels of Baseline-Predicted Cardiovascular Risk: The Look AHEAD Study.The American journal of medicine · 2021Article
- Circulating microRNAs fluctuations in exercise-induced cardiac remodeling: A systematic review.American journal of translational research · 2021Review
- Adaptive response triggered by the repeated SCUBA diving is reflected in cardiovascular, muscular, and immune biomarkers.Physiological reports · 2021Article
- Low-intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults.Physiological reports · 2020Article
- Scaling left ventricular mass in adolescent female soccer players.BMC pediatrics · 2020Article
- Swimming exercise inhibits myocardial ER stress in the hearts of aged mice by enhancing cGMP‑PKG signaling.Molecular medicine reports · 2020Article
- Exercise and Hyperlipidemia.Advances in experimental medicine and biology · 2020Review
- Review
- The effect of the behavior modification program Dietary Approaches to Stop Hypertension (DASH) on reducing the risk of hypertension among elderly patients in the rural community of Phayao, Thailand.Journal of multidisciplinary healthcare · 2019Article
- Resistance Isn't Futile: The Physiological Basis of the Health Effects of Resistance Exercise in Individuals With Type 1 Diabetes.Frontiers in endocrinology · 2019Review
- Expression of striated activator of rho-signaling in human skeletal muscle following acute exercise and long-term training.Physiological reports · 2018Article
- Cardiorespiratory Fitness and Atherosclerosis: Recent Data and Future Directions.Current atherosclerosis reports · 2016Review
- Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs.American journal of physiology. Heart and circulatory physiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are alarming increases in the incidence of obesity, insulin resistance, type II diabetes, and cardiovascular disease. The risk of these diseases is significantly reduced by appropriate lifestyle modifications such as increased physical activity. However, the exact mechanisms by which exercise influences the development and progression of cardiovascular disease are unclear. In this paper we review some important exercise-induced changes in cardiac, vascular, and blood tissues and discuss recent clinical trials related to the benefits of exercise. We also discuss the roles of boosting antioxidant levels, consequences of epicardial fat reduction, increases in expression of heat shock proteins and endoplasmic reticulum stress proteins, mitochondrial adaptation, and the role of sarcolemmal and mitochondrial potassium channels in the contributing to the cardioprotection offered by exercise. In terms of vascular benefits, the main effects discussed are changes in exercise-induced vascular remodeling and endothelial function. Exercise-induced fibrinolytic and rheological changes also underlie the hematological benefits of exercise.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.