ArticleMultiple sclerosis international2012
Treadmill training in multiple sclerosis: can body weight support or robot assistance provide added value? A systematic review.
Article in Multiple sclerosis international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Robot-assisted Gait Training in Patients Affected by Multiple Sclerosis: Rehabilitative Efficacy Evaluation and Comparison With Traditional Methods
Energy Consumption and Cardiorespiratory Load During Walking With and Without Robot-Assistance
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Influence of body weight unloading on human gait characteristics: a systematic review.Journal of neuroengineering and rehabilitation · 2018Pooled it
- Robot-Assisted Gait Training in Patients with Multiple Sclerosis: A Randomized Controlled Crossover Trial.Medicina (Kaunas, Lithuania) · 2021Trial
- Vigorous cool room treadmill training to improve walking ability in people with multiple sclerosis who use ambulatory assistive devices: a feasibility study.BMC neurology · 2020Trial
- Effectiveness of robot-assisted gait training in children with cerebral palsy: a bicenter, pragmatic, randomized, cross-over trial (PeLoGAIT).BMC pediatrics · 2017Trial
- Trial
- A task-oriented circuit training in multiple sclerosis: a feasibility study.BMC neurology · 2014Trial
- Preventive strategies in neuroimmunology.Neurological research and practice · 2026Review
- Lower limb active exoskeletons, exosuits, assistive devices and specifications: a scoping review.Journal of neuroengineering and rehabilitation · 2026Article
- The effect of the LokomatFrontiers in neurology · 2023Review
- Human movement in simulated hypogravity-Bridging the gap between space research and terrestrial rehabilitation.Frontiers in neurology · 2023Review
- Walking with UAN.GO Exoskeleton: Training and Compliance in a Multiple Sclerosis Patient.Neurology international · 2021Article
- Novel velocity estimation for symmetric and asymmetric self-paced treadmill training.Journal of neuroengineering and rehabilitation · 2021Article
- Dalfampridine for Mobility Limitations in People With Multiple Sclerosis May Be Augmented by Physical Therapy: A Non-randomized Two-Group Proof-of-Concept Pilot Study.Frontiers in rehabilitation sciences · 2021Article
- Advanced Robotic Therapy Integrated Centers (ARTIC): an international collaboration facilitating the application of rehabilitation technologies.Journal of neuroengineering and rehabilitation · 2018Observational
- Frontal brain activation changes due to dual-tasking under partial body weight support conditions in older adults with multiple sclerosis.Journal of neuroengineering and rehabilitation · 2017Article
- Human-Robot Interaction: Does Robotic Guidance Force Affect Gait-Related Brain Dynamics during Robot-Assisted Treadmill Walking?PloS one · 2015Article
- Is walking capacity in subjects with multiple sclerosis primarily related to muscle oxidative capacity or maximal muscle strength? A pilot study.Multiple sclerosis international · 2014Article
- Robot-assisted vs. sensory integration training in treating gait and balance dysfunctions in patients with multiple sclerosis: a randomized controlled trial.Frontiers in human neuroscience · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose. This systematic review critically analyzes the literature on the effectiveness of treadmill training (TT), body-weight-supported TT (BWSTT), and robot-assisted TT (RATT) in persons with multiple sclerosis (MS), with focus on gait-related outcome measurements. Method. Electronic databases (Pubmed, Pedro, Web of Science, and Cochrane Library) and reference lists of articles and narrative reviews were searched. Pre-, quasi- and true-experimental studies were included if adult persons with MS were involved in TT, BWSTT, or RATT intervention studies published before 2012. Descriptive analysis was performed and two researchers scored the methodological quality of the studies. Results. 5 true- and 3 preexperimental studies (mean quality score: 66%) have been included. In total 161 persons with MS were involved (TT, BWSTT, or RATT, 6-42 sessions; 2-5x/week; 3-21 weeks). Significant improvements in walking speed and endurance were reported. Furthermore, improvements of step length, double-support time, and Expanded Disability Status Scale were found. Conclusions. There is a limited number of published papers related to TT in persons with MS, concluding that TT, BWSTT, and RATT improve the walking speed and endurance. However, it is not clear what type of TT is most effective. RCTs with larger but more homogeneous populations are needed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.