Evidence map›Paper›PMID 22701112›Full record

ArticleFrontiers in microbiology2012

Genetics Techniques for Thermococcus kodakarensis.

Travis H Hileman, Thomas J Santangelo

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
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  6. A novelProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. The extensive mNature communications · 2024
    Article
  8. Article
  9. Progress and Challenges in Archaeal Genetic Manipulation.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
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  12. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Travis H HilemanDepartment of Microbiology, Center for RNA Biology, Ohio State University Columbus, OH, USA.
Thomas J Santangelo

Funding

Mechanisms of Archaeal Transcription Termination - Administrative SupplementR01GM100329 · NIGMS · OHIO STATE UNIVERSITY · PI SANTANGELO, THOMAS JAMES · 2012 to 2021
$2.5M
A Model Archaeal System: Genetic Tools and Resources for T. kodakarensisR24GM098176 · NIGMS · OHIO STATE UNIVERSITY · PI REEVE, JOHN NEWTON · 2011 to 2014
$1.2M
NIGMS NIH HHS R01 GM100329NIGMS NIH HHS R24 GM098176
6 · The paper itself

Abstract

Thermococcus kodakarensis (T. kodakarensis) has emerged as a premier model system for studies of archaeal biochemistry, genetics, and hyperthermophily. This prominence is derived largely from the natural competence of T. kodakarensis and the comprehensive, rapid, and facile techniques available for manipulation of the T. kodakarensis genome. These genetic capacities are complemented by robust planktonic growth, simple selections, and screens, defined in vitro transcription and translation systems, replicative expression plasmids, in vivo reporter constructs, and an ever-expanding knowledge of the regulatory mechanisms underlying T. kodakarensis metabolism. Here we review the existing techniques for genetic and biochemical manipulation of T. kodakarensis. We also introduce a universal platform to generate the first comprehensive deletion and epitope/affinity tagged archaeal strain libraries.

Indexed as

archaeageneticshyperthermophilicrecombinationThermococcalestranscription

Identifiers

PMID22701112
PMCPMC3370424

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.