Evidence map›Paper›PMID 22701052›Full record

ReviewGenetics2012

Cell polarization and cytokinesis in budding yeast.

Erfei Bi, Hay-Oak Park

Abstract readReview
In one paragraph

Review in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed.

  1. Devising a divisome for synthetic cells.Nature reviews. Chemistry · 2026
    Review
  2. Review
  3. Article
  4. Polarization as a Process: The Potential of Process Ontology for Understanding Cellular Symmetry Breaking.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. The Macroevolution of Filamentation Morphology Across thebioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Roles for the canonical polarity machinery in thebioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Septin Organization and Dynamics for Budding Yeast Cytokinesis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  18. RewiringMetabolic engineering communications · 2024
    Article
  19. Patterning of the cell cortex by Rho GTPases.Nature reviews. Molecular cell biology · 2024
    Review
  20. Article

120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Erfei BiDepartment of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6058, USA. ebi@mail.med.upenn.edu
Hay-Oak Park

Funding

SIGNALING MECHANISMS IN CELL POLARITY IN YEASTR01GM059216 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BI, ERFEI · 1999 to 2012
$3.8M
Regulation of polarized cell growth by GTPasesR01GM076375 · NIGMS · OHIO STATE UNIVERSITY · PI PARK, HAY-OAK · 2006 to 2009
$1.3M
Mechanisms of Cytokinesis in YeastR01GM087365 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BI, ERFEI · 2010 to 2013
$1.2M
NIGMS NIH HHS GM59216NIGMS NIH HHS GM76375NIGMS NIH HHS GM87365NIGMS NIH HHS R01 GM059216NIGMS NIH HHS R01 GM076375NIGMS NIH HHS R01 GM087365
6 · The paper itself

Abstract

Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for generating cell diversity during development. The budding yeast Saccharomyces cerevisiae reproduces by asymmetric cell division, and has thus served as an attractive model for unraveling the general principles of eukaryotic cell polarization and cytokinesis. Polarity development requires G-protein signaling, cytoskeletal polarization, and exocytosis, whereas cytokinesis requires concerted actions of a contractile actomyosin ring and targeted membrane deposition. In this chapter, we discuss the mechanics and spatial control of polarity development and cytokinesis, emphasizing the key concepts, mechanisms, and emerging questions in the field.

Indexed as

Cell PolarityCytokinesisSaccharomycetales

Identifiers

PMID22701052
PMCPMC3374305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.