ArticleAmerican journal of respiratory and critical care medicine2012
Predicting cognitive sequelae in survivors of critical illness with cognitive screening tests.
Article in American journal of respiratory and critical care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Natural History of Cognitive Impairment in Critical Illness Survivors. A Systematic Review.American journal of respiratory and critical care medicine · 2020Pooled it
- Interventions for preventing intensive care unit delirium in adults.The Cochrane database of systematic reviews · 2018Pooled it
- Early rehabilitation to prevent postintensive care syndrome in patients with critical illness: a systematic review and meta-analysis.BMJ open · 2018Pooled it
- One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomised trial.BMJ (Clinical research ed.) · 2013Trial
- Applying the Age-Friendly Health Systems Framework to Promote Adoption and Sustainability of Interventions for Older Adults in the Intensive Care Unit.Journal of gerontological nursing · 2026Review
- Developing a prediction model for cognitive impairment in older adults following critical illness.BMC geriatrics · 2024Article
- Older Adults' Perspectives on Screening for Cognitive Impairment Following Critical Illness: Pre-Implementation Qualitative Study.Critical care explorations · 2023Article
- Post-intensive Care Syndrome.Annals of geriatric medicine and research · 2021Article
- Instruments to measure outcomes of post-intensive care syndrome in outpatient care settings - Results of an expert consensus and feasibility field test.Journal of the Intensive Care Society · 2021Article
- Frailty subtypes and recovery in older survivors of acute respiratory failure: a pilot study.Thorax · 2021Article
- Improvement in Activities of Daily Living during a Nursing Home Stay and One-Year Mortality among Older Adults with Sepsis.Journal of the American Geriatrics Society · 2021Article
- Cystatin C regulates the cytotoxicity of infection-induced endothelial-derived β-amyloid.FEBS open bio · 2020Article
- Challenges in conducting long-term outcomes studies in critical care.Current opinion in critical care · 2019Review
- Cognitive Deficits Following Intensive Care.Deutsches Arzteblatt international · 2019Review
- Early Post-Intensive Care Syndrome among Older Adult Sepsis Survivors Receiving Home Care.Journal of the American Geriatrics Society · 2019Article
- Enhancing Recovery From Sepsis: A Review.JAMA · 2018Review
- Improving Long-Term Outcomes After Sepsis.Critical care clinics · 2018Review
- Mechanisms involved in brain dysfunction in mechanically ventilated critically ill patients: implications and therapeutics.Annals of translational medicine · 2018Review
- Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients.Annals of intensive care · 2017Article
- Observational
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleSurvivors of critical illness have a high rate of cognitive impairments that may persist years after hospital discharge. Data are lacking regarding whether cognitive screening tests administered at hospital discharge can be used to predict which critically ill patients are likely to have long-term cognitive sequelae.
objectivesThis prospective study assessed whether two cognitive screening tests, the Mini-Mental State Examination (MMSE) and Mini-Cog, administered at hospital discharge, predict cognitive sequelae in survivors of critical illness 6 months after hospital discharge.
methodsSeventy critically ill patients completed the MMSE and Mini-Cog just before hospital discharge. Of these 70 patients, 53 completed a neuropsychological battery 6 months after hospital discharge. MEASUREMENTS AND MAIN
resultsAt hospital discharge, 45 patients (64%) had impaired performance on the MMSE (score < 27, mean = 24.4) and 32 (45%) on the Mini-Cog. Twenty-seven patients (39%) were impaired on both the MMSE and Mini-Cog, whereas only 20 patients (28%) had scores in the normal range on both tests. Cognitive sequelae occurred in 57% of survivors (30 of 53) at 6 months, with predominant dysfunction in the memory (38%) and executive (36%) domains. Logistic regression analyses showed that neither the MMSE nor the Mini-Cog predicted cognitive sequelae at 6 months.
conclusionsA large number of critically ill survivors had cognitive impairments, as assessed by the MMSE and Mini-Cog, at hospital discharge. However, the MMSE and Mini-Cog scores did not predict long-term cognitive sequelae at 6-month follow-up and cannot be used as surrogate endpoints for long-term cognitive impairment.
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