Evidence map›Paper›PMID 22700831›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2012

Nosocomial diarrhea: evaluation and treatment of causes other than Clostridium difficile.

Christopher R Polage, Jay V Solnick, Stuart H Cohen

Abstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Article
  2. Article
  3. Adjunctive use ofTranslational gastroenterology and hepatology · 2026
    Article
  4. Article
  5. Article
  6. Curbing inappropriateAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  7. Article
  8. Article
  9. Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  10. Article
  11. Review
  12. Impact of the Reverse 2-Step Algorithm forOpen forum infectious diseases · 2024
    Article
  13. Article
  14. Derivation and internal validation of the multivariate toxigenicAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  15. Article
  16. Prevalence of Non-ToxigenicAntibiotics (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Bacterial Foodborne Illness in Malaysia:The Malaysian journal of medical sciences : MJMS · 2023
    Review
  19. Bezlotoxumab Therapy for RecurrentCrohn's & colitis 360 · 2022
    Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher R PolageDepartment of Pathology and Laboratory Medicine, Division of Infectious Diseases, University of California, Davis Medical Center, Sacramento, USA. christopher.polage@ucdmc.ucdavis.edu
Jay V Solnick
Stuart H Cohen

Funding

UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
UC Davis Clinical and Translational Science CenterUL1TR000002 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2012 to 2015
$12.2M
UC Davis Clinical and Translational Science CenterKL2RR024144 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$3.1M
NCATS NIH HHS UL1 TR000002NCRR NIH HHS KL2 RR024144NCRR NIH HHS UL1 RR024146
6 · The paper itself

Abstract

Diarrhea is common among hospitalized patients but the causes are distinct from those of diarrhea in the community. We review existing data about the epidemiology of nosocomial diarrhea and summarize recent progress in understanding the mechanisms of diarrhea. Clinicians should recognize that most cases of nosocomial diarrhea have a noninfectious etiology, including medications, underlying illness, and enteral feeding. Apart from Clostridium difficile, the frequency of infectious causes such as norovirus and toxigenic strains of Clostridium perfringens, Klebsiella oxytoca, Staphylococcus aureus, and Bacteroides fragilis remains largely undefined and test availability is limited. Here we provide a practical approach to the evaluation and management of nosocomial diarrhea when tests for C. difficile are negative.

Indexed as

Bacterial InfectionsCross InfectionDiarrheaDrug-Related Side Effects and Adverse ReactionsHumansVirus Diseases

Identifiers

PMID22700831
PMCPMC3657522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.