ArticleEuropean radiology2012
Low-dose CT of the lung: potential value of iterative reconstructions.
Article in European radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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55 citing papers in PubMed, 150 citations in OpenAlex.
- Exploration of thoracoabdominal aortic mixed reality optimisation and its clinical application value in type A aortic dissection.European radiology · 2023Trial
- Improving image quality with model-based iterative reconstruction at quarter of nominal dose in upper abdominal CT.The British journal of radiology · 2019Trial
- High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume.European radiology · 2014Trial
- Reducing radiation dose in the diagnosis of pulmonary embolism using adaptive statistical iterative reconstruction and lower tube potential in computed tomography.European radiology · 2014Trial
- Impact of iterative reconstruction on CT coronary calcium quantification.European radiology · 2013Trial
- Comparative assessment of image quality and radiation dose: spectral purification computed tomography (Sn100kV) with adaptive iterative reconstruction for tuberculosis follow-up.Journal of thoracic disease · 2026Article
- Aortic valve and coronary artery calcium scoring: impact of half- versus standard-dose protocols.La Radiologia medica · 2025Article
- Article
- Effects of tube voltage, radiation dose and adaptive statistical iterative reconstruction strength level on the detection and characterization of pulmonary nodules in ultra-low-dose chest CT.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Article
- A highly accurate quantum optimization algorithm for CT image reconstruction based on sinogram patterns.Scientific reports · 2023Article
- Quantitative measurements of emphysema in ultra-high resolution computed tomography using model-based iterative reconstruction in comparison to that using hybrid iterative reconstruction.Physical and engineering sciences in medicine · 2022Article
- Quantum Iterative Reconstruction for Low-Dose Ultra-High-Resolution Photon-Counting Detector CT of the Lung.Diagnostics (Basel, Switzerland) · 2022Article
- Low-dose CT with tin filter combined with iterative metal artefact reduction for guiding lung biopsy.Quantitative imaging in medicine and surgery · 2022Article
- Chest CT screening in patients with overweight or obesity using spectral shaping at 150 kVp: compared with 120 kVp protocol and spectral shaping at 100 kVp protocol.Japanese journal of radiology · 2020Article
- Influence of acquisition settings and radiation exposure on CT lung densitometry-An anthropomorphic ex vivo phantom study.PloS one · 2020Article
- A practical and adaptive approach to lung cancer screening: a review of international evidence and position on CT lung cancer screening in the Singaporean population by the College of Radiologists Singapore.Singapore medical journal · 2019Review
- Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study.European radiology · 2019Article
- Diagnosis of urine leakage after bladder repair: a prospective comparative study of ultra-low-dose CT cystography and conventional retrograde cystography.La Radiologia medica · 2019Article
- Volumetric assessment of solid pulmonary nodules on ultralow-dose CT: a phantom study.Journal of thoracic disease · 2019Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo prospectively assess the impact of sinogram-affirmed iterative reconstruction (SAFIRE) on image quality of nonenhanced low-dose lung CT as compared to filtered back projection (FBP).
methodsNonenhanced low-dose chest CT (tube current-time product: 30 mAs) was performed on 30 patients at 100 kVp and on 30 patients at 80 kVp. Images were reconstructed with FBP and SAFIRE. Two blinded, independent readers measured image noise; two readers assessed image quality of normal anatomic lung structures on a five-point scale. Radiation dose parameters were recorded.
resultsImage noise in datasets reconstructed with FBP (57.4 ± 15.9) was significantly higher than with SAFIRE (31.7 ± 9.8, P < 0.001). Image quality was significantly superior with SAFIRE than with FBP (P < 0.01), without significant difference between FBP at 100 kVp and SAFIRE at 80 kVp (P = 0.68). Diagnostic image quality was present with FBP in 96% of images at 100 kVp and 88% at 80 kVp, and with SAFIRE in 100% at 100 kVp and 98% at 80 kVp. There were significantly more datasets with diagnostic image quality with SAFIRE than with FBP (P < 0.01). Mean CTDI(vol) and effective doses were 1.5 ± 0.7 mGy·cm and 0.7 ± 0.2 mSv at 100 kVp, and 1.4 ± 2.8 mGy · cm and 0.5 ± 0.2 mSv at 80 kVp (P < 0.001, both).
conclusionsUse of SAFIRE in low-dose lung CT reduces noise, improves image quality, and renders more studies diagnostic as compared to FBP. KEY POINTS: Low-dose computed tomography is an important thoracic investigation tool. Radiation dose can be less than 1 mSv with iterative reconstructions. Iterative reconstructions render more low-dose lung CTs diagnostic compared to conventional reconstructions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.