ArticleDer Orthopade2012
[Risk factors for failed cleansing following periprosthetic delayed hip prosthesis infection].
Article in Der Orthopade, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Intravenous drug abuse is a risk factor in the failure of two-stage treatment for infected total hip arthroplasty.The Kaohsiung journal of medical sciences · 2017Article
- Outcome of total knee replacement following explantation and cemented spacer therapy.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2016Article
- [Etiology and classification of septic coxitis].Der Unfallchirurg · 2012Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite extensive cleansing concepts recurrent infections are relatively common especially for infections of hip prostheses. The aim of this retrospective study was to identify factors which hinder cleansing and facilitate recurrence. MATERIALS AND
methodsThis study included 40 patients with periprosthetic delayed hip prosthesis infection who had been treated with the aim of infection cleansing between 2006 and 2008. Infection cleansing was carried out using a standardized treatment regimen with two and multiple phase reimplantation of the hip prosthesis following successful pathogen eradication. A clinical course follow-up was carried out after 2 years.
resultsOf the patients 18 (45%) were free of recurrence following successful eradication and reimplantation of the prosthesis and 5 (12.5%) suffered recurrence of infection after primarily successful revision prosthesis. In 17 patients (42.5%) treatment was switched to an alternative procedure primarily due to an uncleansable infection. In the group of patients with recurrent infections or untreatable infection, resistant pathogens could be detected significantly more often (p=0.001), in particular methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE) and highly resistant Pseudomonas. This group had a significantly worse American Society of Anesthesiologists (ASA) score (p = 0.002). The number of surgical interventions in this group was significantly higher.
conclusionsA poorer general physical condition and resistant infectious pathogens are the main risk factors for recurrent infections following prosthesis reimplantation. Therefore, a different treatment concept should be used for polymorbid patients with resistant pathogen infections.
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