Trial reportEuropean journal of nuclear medicine and molecular imaging2012
Evaluation of ischaemia in obese patients: feasibility and accuracy of a low-dose protocol with a cadmium-zinc telluride camera.
Trial report in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 47 citations in OpenAlex.
- Comparison between stress myocardial perfusion SPECT recorded with cadmium-zinc-telluride and Anger cameras in various study protocols.European journal of nuclear medicine and molecular imaging · 2013Trial
- Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted filter parameters.EJNMMI research · 2024Article
- New Generation SPECT Cameras Based on Cadmium-Zinc Telluriide Technology.Annals of nuclear cardiology · 2024Review
- A Pitfall of Simultaneous Acquisition StressAnnals of nuclear cardiology · 2022Article
- Comparison between NJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- MPI in the era of CZT cameras: Absolute numbers are still better than relative figures.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Myocardial perfusion imaging in overweight patients and women: Is it CZT good enough?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Left ventricular mechanical dyssynchrony assessment in obese patients using the cadmium-zinc telluride SPECT camera.The international journal of cardiovascular imaging · 2020Article
- Automatic evaluation of myocardial perfusion on SPECT: Need for "Normality".Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Myocardial perfusion imaging in extreme obesity: Leveraging modern technologies to meet a modern challenge.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- CMR stress testing in a patient with morbid obesity (BMI 58 kg/mBMC cardiovascular disorders · 2018Article
- The radiation dose to overweighted patients undergoing myocardial perfusion SPECT can be significantly reduced: validation of a linear weight-adjusted activity administration protocol.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Performance of cardiac cadmium-zinc-telluride gamma camera imaging in coronary artery disease: a review from the cardiovascular committee of the European Association of Nuclear Medicine (EANM).European journal of nuclear medicine and molecular imaging · 2016Review
- Normal Databases for the Relative Quantification of Myocardial Perfusion.Current cardiovascular imaging reports · 2016Article
- Newer generation cameras are preferred.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Prognostic value of normal stress-only myocardial perfusion imaging: a comparison between conventional and CZT-based SPECT.European journal of nuclear medicine and molecular imaging · 2016Article
- Prognostic evaluation in obese patients using a dedicated multipinhole cadmium-zinc telluride SPECT camera.The international journal of cardiovascular imaging · 2016Article
- Impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion SPECT using cadmium-zinc telluride detectors in the rat.EJNMMI physics · 2015Article
- Feasibility and diagnostic accuracy of exercise treadmill nitrogen-13 ammonia PET myocardial perfusion imaging of obese patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Stress-first protocol for myocardial perfusion SPECT imaging with semiconductor cameras: high diagnostic performances with significant reduction in patient radiation doses.European journal of nuclear medicine and molecular imaging · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeObesity is a significant and independent risk factor for cardiovascular disease, and assessing ischaemia in obese patients is clinically important but sometimes difficult because of imaging artefacts. The aim of this study was to evaluate the feasibility and diagnostic accuracy of stress/rest imaging with a cadmium-zinc telluride (CZT) camera using a low-dose protocol in a series of consecutive obese patients referred for the evaluation of coronary artery disease.
methodsWe considered 148 consecutive obese patients (mean BMI 39 ± 7 kg/m(2)) with known or suspected coronary artery disease referred to our laboratory for stress/rest myocardial perfusion imaging. A subgroup of 103 of the 148 patients underwent invasive coronary angiography for clinical reasons. All patients underwent a single-day stress/rest low-dose ultrafast protocol. Patients were injected with (99m)Tc-tetrofosmin at a dose in the range 185-222 MBq during bicycle exercise or dipyridamole stress, and underwent the first scan with an acquisition time of 7 min starting 15 min after the end of the stress. The rest scan with an acquisition time of 6 min was started from 30 to 45 min after (99m)Tc-tetrofosmin injection at a dose in the range 370-444 MBq. Images were visually inspected, and the summed stress score (SSS) and summed rest score (SRS) were obtained.
resultsImage quality was graded very good or excellent in all patients. Of the 103 patients who underwent coronary angiography, 12 (12 %), 26 (25 %) and 56 (54 %) showed one-, two- and three-vessel disease, and 9 showed normal coronary vessels. In the 103 patients submitted to coronary angiography, the mean SSS and SRS were 7 ± 6 and 2 ± 3, respectively. Semiquantitative regional and global SSS was a good discriminant of coronary artery disease and the area under the overall ROC curve was 0.848 (95 % CI 0.723-0.975).
conclusionIn obese patients, a single-day stress/rest low-dose ultrafast protocol with a CZT camera is clinically feasible and provides high image quality.
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