ReviewJournal of gastroenterology2012
An update of the role of nutritional therapy in the management of Crohn's disease.
Review in Journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- CONSORT: Different End-Points of Preoperative Nutrition and Outcome of Bowel Resection of Crohn Disease: A Randomized Clinical Trial.Medicine · 2015Trial
- Effect of short-term partial enteral nutrition on the treatment of younger patients with severe Crohn's disease.Gut and liver · 2015Trial
- Microbiome-microRNA interactions in inflammatory bowel disease: insights from metagenomic and transcriptomic data analysis.Gastroenterology and hepatology from bed to bench · 2025Article
- Diagnostic interval of inflammatory bowel disease in Chinese children and its relationship with growth parameters: a retrospective study.Frontiers in pediatrics · 2025Article
- The impact of age, disease severity, and BMI on bone health and growth in children and young people with Crohn's disease.JPGN reports · 2024Article
- Evaluation of nutritional status using bioelectrical impedance analysis in patients with inflammatory bowel disease.Intestinal research · 2022Article
- Laparoscopy for Crohn's disease: A comprehensive exploration of minimally invasive surgical techniques.World journal of gastrointestinal surgery · 2021Article
- Exclusive enteral nutrition with concomitant early thiopurine use was effective in maintaining steroid-free remission in a Southeast Asian cohort of children with Crohn's disease.BMC gastroenterology · 2018Article
- A Challenging Treatment Decision for a Rare Association: Case Report of Familial Turcot Syndrome With Fistulizing Crohn's Disease.Frontiers in pediatrics · 2018Article
- Effect of the Baseline Vitamin D Level on Growth Outcome in Pediatric Crohn Disease.Pediatric gastroenterology, hepatology & nutrition · 2017Article
- Outcomes of exclusive enteral nutrition in paediatric Crohn's disease.European journal of clinical nutrition · 2017Article
- Safety and Efficacy of Exclusive Enteral Nutrition for Percutaneously Undrainable Abdominal Abscesses in Crohn's Disease.Gastroenterology research and practice · 2017Article
- Article
- Features and perspectives of MR enterography for pediatric Crohn disease assessment.La Radiologia medica · 2016Article
- Advances in nutritional therapy in inflammatory bowel diseases: Review.World journal of gastroenterology · 2016Review
- Development and Application of a Plant-Based Diet Scoring System for Japanese Patients with Inflammatory Bowel Disease.The Permanente journal · 2016Article
- Short-Term Efficacy of Exclusive Enteral Nutrition in Pediatric Crohn's Disease: Practice in China.Gastroenterology research and practice · 2015Article
- Crohn's disease and growth deficiency in children and adolescents.World journal of gastroenterology · 2014Review
- Risk factors for relapse and surgery rate in children with Crohn's disease.European journal of pediatrics · 2014Article
- Preoperative exclusive enteral nutrition reduces the postoperative septic complications of fistulizing Crohn's disease.European journal of clinical nutrition · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crohn's disease is an increasingly global health concern. Currently without a cure, it significantly alters the quality of life of Crohn's disease sufferers and places a heavy financial burden on the community. Recent reports show that the rising prevalence of Crohn's disease is no longer confined to Western countries, with considerable increases seen particularly in Asia. Nutritional problems are often associated with Crohn's disease, most notably in the paediatric population, with underweight and stunting commonly seen at presentation. In addition, linear growth retardation and pubertal delay can also manifest in these younger patients. Therefore, exclusive enteral nutrition has been used as a therapeutic option to treat Crohn's disease, in part to address the nutritional complications of the disease. Exclusive enteral nutrition can improve nutrition as well as induce remission at a rate equivalent to corticosteroids. It is safe particularly with long-term use and can induce mucosal healing, considered the gold standard for therapy, at a rate superior to corticosteroids. Exclusive enteral nutrition has thus become the preferred therapeutic option in many centres for the treatment of paediatric Crohn's disease. This review discusses the role of exclusive enteral nutrition as a therapeutic option for the treatment of Crohn's disease, as well as the latest findings into its mechanisms of action.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.