ArticleDiabetes care2012
Association of prediabetes and diabetes with stroke symptoms: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study.
Article in Diabetes care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Changing patterns of stroke multimorbidity in India: A longitudinal analysis of WHO-SAGE data (2007-2020).The Indian journal of medical research · 2026Article
- Isolated non-specific electrocardiographic ST-T abnormalities and risk of incident heart failure and its subtypes.Heart (British Cardiac Society) · 2026Article
- Machine Learning Approaches for Stroke Risk Prediction: Findings from the Suita Study.Journal of cardiovascular development and disease · 2024Article
- Atherosclerotic cardiovascular disease events among adults with high predicted risk without established risk factors.American journal of preventive cardiology · 2024Article
- Identifying diagnostic indicators for type 2 diabetes mellitus from physical examination using interpretable machine learning approach.Frontiers in endocrinology · 2024Article
- D-dimer and the risk of hypertension: The REasons for Geographic And Racial Differences in Stroke Cohort Study.Research and practice in thrombosis and haemostasis · 2023Article
- Elevated depressive symptoms and risk of all-cause and cardiovascular mortality among adults with and without diabetes: The REasons for Geographic And Racial Differences in Stroke (REGARDS) study.Journal of diabetes and its complications · 2020Article
- Examining the causal mediating role of brain pathology on the relationship between diabetes and cognitive impairment: the Cardiovascular Health Study.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2020Article
- Does the Association of Diabetes With Stroke Risk Differ by Age, Race, and Sex? Results From the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.Diabetes care · 2019Article
- A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study.BMC medical genomics · 2019Article
- Interaction of Sex and Diabetes on Outcome After Ischemic Stroke.Frontiers in neurology · 2018Article
- Diabetes, diabetes severity, and coronary heart disease risk equivalence: REasons for Geographic and Racial Differences in Stroke (REGARDS).American heart journal · 2016Article
- Stroke symptoms and risk for incident coronary heart disease in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.International journal of cardiology · 2016Article
- Ischemic stroke in prediabetic patients.Journal of neurology · 2014Article
- Effect of diabetes on stroke symptoms and mortality: Lessons from a recent large population-based cohort study.Journal of diabetes investigation · 2014Article
- The role of HbA1c determination in detecting unknown glucose disturbances in ischemic stroke.PloS one · 2014Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveStroke symptoms among individuals reporting no physician diagnosis of stroke are associated with an increased risk of future stroke. Few studies have assessed whether individuals with diabetes or prediabetes, but no physician diagnosis of stroke, have an increased prevalence of stroke symptoms. RESEARCH DESIGN AND
methodsThis study included 25,696 individuals aged ≥ 45 years from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study who reported no history of stroke or transient ischemic attack at baseline (2003-2007). Glucose measurements, medication use, and self-reported physician diagnosis were used to categorize participants into diabetes, prediabetes, or normal glycemia groups. The presence of six stroke symptoms was assessed using a validated questionnaire.
resultsThe prevalence of any stroke symptom was higher among participants with diabetes (22.7%) compared with those with prediabetes (15.6%) or normal glycemia (14.9%). In multivariable models, diabetes was associated with any stroke symptom (prevalence odds ratio [POR] 1.28 [95% CI 1.18-1.39]) and two or more stroke symptoms (1.26 [1.12-1.43]) compared with normal glycemia. In analyses of individual stroke symptoms, diabetes was associated with numbness (1.15 [1.03-1.29]), vision loss (1.52 [1.31-1.76]), half-vision loss (1.54 [1.30-1.84]), and lost ability to understand people (1.34 [1.12-1.61]) after multivariable adjustment. No association was present between prediabetes and stroke symptoms.
conclusionsIn this population-based study, almost one in four individuals with diabetes reported stroke symptoms, which suggests that screening for stroke symptoms in diabetes may be warranted.
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