Evidence map›Paper›PMID 22699291›Full record

ArticleDiabetes care2012

Independent effect of ethnicity on glycemia in South Asians and white Europeans.

Samiul A Mostafa, Melanie J Davies, David R Webb, Balasubramanian Thiagarajan Srinivasan, Laura J Gray, Kamlesh Khunti

Open access · hybridAbstract read
In one paragraph

Article in Diabetes care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Screening for type 2 diabetes mellitus.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Alternative type 2 diabetes screening tests may reduce the number of U.S. adults with undiagnosed diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2020
    Article
  10. Article
  11. Article
  12. Review
  13. Geographic Clustering of Cardiometabolic Risk Factors in Metropolitan Centres in France and Australia.International journal of environmental research and public health · 2016
    Article
  14. Article
  15. Is There a Role for HbA1c in Pregnancy?Current diabetes reports · 2016
    Review
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Samiul A MostafaDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK. samiul.mostafa@uhl-tr.nhs.uk
Melanie J Davies
David R Webb
Balasubramanian Thiagarajan Srinivasan
Laura J Gray
Kamlesh Khunti
University of Leicester · GB

Funding

Department of Health
6 · The paper itself

Abstract

objectiveHbA(1c) levels are higher in most ethnic groups compared with white Europeans (WEs) independent of glycemic control. This comparison has not been performed between South Asians (SAs) and WEs. We analyzed the independent effect of ethnicity on HbA(1c) and fasting and 2-h plasma glucose (FPG and 2 hrPG, respectively) between these groups. RESEARCH DESIGN AND

methodsAnalysis of the ADDITION-Leicester study, in which 4,688 WEs and 1,352 SAs underwent oral glucose tolerance testing, HbA(1c), and other risk factor measurements.

resultsSignificant associations with HbA(1c) included ethnicity, FPG, 2 hrPG, and homeostasis model assessment of β-cell function (P < 0.001); age and sex (P < 0.01); and fasting insulin and potassium (P < 0.05). After adjusting for these and other risk factors, SAs demonstrated higher HbA(1c) (6.22 and 6.02%, mean difference 0.20%, 0.10-0.30, P < 0.001), FPG (5.15 and 5.30 mmol/L, mean difference 0.15 mmol/L, 0.09-0.21, P < 0.001), and 2 hrPG (5.82 and 6.57 mmol/L, mean difference 0.75 mmol/L, 0.59-0.92, P < 0.001) compared with WEs, respectively.

conclusionsHbA(1c), FPG, and 2 hrPG levels were higher in SAs independent of factors affecting glycemic control.

Indexed as

Asian PeopleBlood GlucoseFemaleGlucose Tolerance TestGlycated HemoglobinHumansMaleWhite PeopleBlood GlucoseGlycated Hemoglobin

Identifiers

PMID22699291
PMCPMC3402276
OpenAlexW2036591017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.