ReviewTissue engineering. Part B, Reviews2012
Strategies to improve regeneration of the soft palate muscles after cleft palate repair.
Review in Tissue engineering. Part B, Reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis.Development (Cambridge, England) · 2023Article
- TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.eLife · 2022Article
- Effect of niche components on masseter satellite cell differentiation on fibrin coatings.European journal of oral sciences · 2022Article
- Orofacial Cleft and Mandibular Prognathism-Human Genetics and Animal Models.International journal of molecular sciences · 2022Review
- Fibrin with Laminin-Nidogen Reduces Fibrosis and Improves Soft Palate Regeneration Following Palatal Injury.Biomolecules · 2021Article
- The biomechanical evaluation of magnetic forces to drive osteogenesis in newborn's with cleft lip and palate.Journal of materials science. Materials in medicine · 2020Article
- Orofacial Muscles: Embryonic Development and Regeneration after Injury.Journal of dental research · 2020Review
- Regulatory Mechanisms of Soft Palate Development and Malformations.Journal of dental research · 2019Review
- Article
- WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development.Development (Cambridge, England) · 2018Article
- Morphological and molecular comparisons between tibialis anterior muscle and levator veli palatini muscle: A preliminary study on their augmentation potential.Experimental and therapeutic medicine · 2018Article
- The Dlx5-FGF10 signaling cascade controls cranial neural crest and myoblast interaction during oropharyngeal patterning and development.Development (Cambridge, England) · 2017Article
- Effect of Dissection and Reconstruction of Palatal Muscles on Morphological Features and Ultrastructure of the Oral Musculature in Cats.BioMed research international · 2016Article
- Dental and Nondental Stem Cell Based Regeneration of the Craniofacial Region: A Tissue Based Approach.Stem cells international · 2016Review
- Isolation and Characterization of Satellite Cells from Rat Head Branchiomeric Muscles.Journal of visualized experiments : JoVE · 2015Article
- A Comprehensive Study of Soft Palate Development in Mice.PloS one · 2015Article
- TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate.Development (Cambridge, England) · 2014Article
- A rat model for muscle regeneration in the soft palate.PloS one · 2013Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Children with a cleft in the soft palate have difficulties with speech, swallowing, and sucking. These patients are unable to separate the nasal from the oral cavity leading to air loss during speech. Although surgical repair ameliorates soft palate function by joining the clefted muscles of the soft palate, optimal function is often not achieved. The regeneration of muscles in the soft palate after surgery is hampered because of (1) their low intrinsic regenerative capacity, (2) the muscle properties related to clefting, and (3) the development of fibrosis. Adjuvant strategies based on tissue engineering may improve the outcome after surgery by approaching these specific issues. Therefore, this review will discuss myogenesis in the noncleft and cleft palate, the characteristics of soft palate muscles, and the process of muscle regeneration. Finally, novel therapeutic strategies based on tissue engineering to improve soft palate function after surgical repair are presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.