ArticleBrain pathology (Zurich, Switzerland)2012
A 28 year old lady with a pituitary mass.
Article in Brain pathology (Zurich, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Lymphocytic infundibulo-neurohypophysitis: a clinical overview.Endocrine · 2015Review
- Invasive Growth Hormone Producing Pituitary Adenoma With Lymphocytic Infiltration: A Case Report and Literature Review.Iranian journal of cancer prevention · 2015Article
- Update on hypophysitis and TTF-1 expressing sellar region masses.Brain pathology (Zurich, Switzerland) · 2013Review
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Authors and funding
3 authors.
Funding
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Abstract
We present a case of an atypical pituitary adenoma with prominent lymphocyte infiltration and germinal center formation. Histologically, the tumor revealed clusters of large pleomorphic cells with vesicular nuclei, prominent nucleoli, smudgy chromatin, and abundant eosinophilic cytoplasm. There was heavy lymphocyte infiltration and prominent germinal center formation. Mitoses were rare, and the Ki-67 index was 15%. The lymphocytes were composed of both CD3-positive T lymphocytes and CD20-positive B-cells. The diagnosis was atypical pituitary adenoma. Germinal centers have not previously been reported in these tumors. It is important to correlate histology and immunohistochemistry to differentiate this adenoma from other pituitary lesions with prominent lymphocyte infiltration, such as germinoma and lymphocytic hypophysitis.
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