Evidence map›Paper›PMID 22696426›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Live-cell imaging of cyclopropene tags with fluorogenic tetrazine cycloadditions.

Jun Yang, Jolita Šečkutė, Christian M Cole, Neal K Devaraj

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. A Fluorogenic Hydrazino-Pictet-Spengler Reaction in Live Cells.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Article
  8. Fluorogenic Coumarins Activated via Bioorthogonal Reactions.The Journal of organic chemistry · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Minimalist TetrazineJournal of the American Chemical Society · 2024
    Article
  13. Bioorthogonal Reactions in Bioimaging.Topics in current chemistry (Cham) · 2024
    Review
  14. Trifunctional Saxitoxin Conjugates for Covalent Labeling of Voltage-Gated Sodium Channels.Chembiochem : a European journal of chemical biology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun YangDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Jolita Šečkutė
Christian M Cole
Neal K Devaraj

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Fast in vivo CLICK chemistries for PET imagingK01EB010078 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEVARAJ, NEAL KRISHNA · 2010 to 2014
$852k
NIBIB NIH HHS K01 EB010078NIBIB NIH HHS K01EB010078NINDS NIH HHS P30 NS047101
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Boron CompoundsCell Line, TumorCell SurvivalCyclopropanesFluorescent DyesHumansHydrocarbons, AromaticMicroscopy, ConfocalPhospholipids4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsCyclopropanescyclopropeneFluorescent DyesHydrocarbons, AromaticPhospholipids

Identifiers

PMID22696426
PMCPMC3431913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.