Evidence map›Paper›PMID 22695735›Full record

ReviewCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2012

The role of obesity in cancer survival and recurrence.

Wendy Demark-Wahnefried, Elizabeth A Platz, Jennifer A Ligibel, Cindy K Blair, Kerry S Courneya, Jeffrey A Meyerhardt, Patricia A Ganz, Cheryl L Rock, Kathryn H Schmitz, Thomas Wadden and 8 more

Abstract readReview
In one paragraph

Review in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Wendy Demark-WahnefriedDepartment of Nutrition Sciences, University of Alabama at Birmingham, Alabama 35294, USA. demark@uab.edu
Elizabeth A Platz
Jennifer A Ligibel
Cindy K Blair
Kerry S Courneya
Jeffrey A Meyerhardt
Patricia A Ganz
Cheryl L Rock
Kathryn H Schmitz
Thomas Wadden
Errol J Philip
Bruce Wolfe
Susan M Gapstur
Rachel Ballard-Barbash
Anne McTiernan
Lori Minasian
Linda Nebeling
Pamela J Goodwin

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Cancer Prevention & Control Training ProgramR25CA047888 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DEMARK-WAHNEFRIED, WENDY, MENESES, KAREN M · 1988 to 2016
$11.2M
Reducing Breast Cancer Recurrence with Weight Loss: A Vanguard TrialR01CA148791 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ROCK, CHERYL L · 2010 to 2013
$4.9M
UAB Cancer Prevention and Control Training Program (T32)T32CA047888 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Ritu Aneja, Ellen Mary Lavoie Smith · 2018 to 2026
$3.2M
NCI NIH HHS CA047888NCI NIH HHS CA13148NCI NIH HHS CA148791NCI NIH HHS P30 CA013148NCI NIH HHS R01 CA148791NCI NIH HHS R25 CA047888NCI NIH HHS T32 CA047888
6 · The paper itself

Abstract

Obesity and components of energy imbalance, that is, excessive energy intake and suboptimal levels of physical activity, are established risk factors for cancer incidence. Accumulating evidence suggests that these factors also may be important after the diagnosis of cancer and influence the course of disease, as well as overall health, well-being, and survival. Lifestyle and medical interventions that effectively modify these factors could potentially be harnessed as a means of cancer control. However, for such interventions to be maximally effective and sustainable, broad sweeping scientific discoveries ranging from molecular and cellular advances, to developments in delivering interventions on both individual and societal levels are needed. This review summarizes key discussion topics that were addressed in a recent Institute of Medicine Workshop entitled, "The Role of Obesity in Cancer Survival and Recurrence"; discussions included (i) mechanisms associated with obesity and energy balance that influence cancer progression; (ii) complexities of studying and interpreting energy balance in relation to cancer recurrence and survival; (iii) associations between obesity and cancer risk, recurrence, and mortality; (iv) interventions that promote weight loss, increased physical activity, and negative energy balance as a means of cancer control; and (v) future directions.

Indexed as

AnimalsHumansIncidenceLife StyleNeoplasm Recurrence, LocalNeoplasmsObesityRisk FactorsSurvival AnalysisWeight Loss

Identifiers

PMID22695735
PMCPMC3415558

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.