Evidence map›Paper›PMID 22695159›Full record

ArticleClinical and vaccine immunology : CVI2012

Comparison of mother and child antibodies that target high-molecular-mass Toxoplasma gondii antigens by immunoblotting improves neonatal diagnosis of congenital toxoplasmosis.

Coralie L'Ollivier, Martine Wallon, Benoit Faucher, Renaud Piarroux, François Peyron, Jacqueline Franck

Open access · diamondAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Laboratory Diagnosis of Congenital Toxoplasmosis.Journal of clinical microbiology · 2016
    Review
  10. Article
  11. Observational
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Coralie L'OllivierLaboratoire de Parasitologie et Mycologie, Centre Hospitalo-Universitaire de la Timone, Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France. coralie.l'ollivier@gmail.com
Martine Wallon
Benoit Faucher
Renaud Piarroux
François Peyron
Jacqueline Franck
Assistance Publique Hôpitaux de Marseille · FRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective study proposes a new reading of immunoblotting (IB) in the diagnosis of congenital toxoplasmosis. Our findings demonstrate that a three-IgM-band association at 75, 90, and 100 kDa called the IgM triplet increases the sensitivity to 95.8% when combined with prenatal and serological neonatal tests.

Indexed as

Antigens, ProtozoanAntibodies, ProtozoanFemaleHumansImmunoblottingImmunoglobulin MInfant, NewbornMolecular WeightPregnancyRetrospective StudiesSensitivity and SpecificitySerologic TestsToxoplasmaToxoplasmosis, CongenitalAntibodies, ProtozoanAntigens, ProtozoanImmunoglobulin M

Identifiers

PMID22695159
PMCPMC3416078
OpenAlexW2078649932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.