Evidence map›Paper›PMID 22694853›Full record

ArticleHealth and quality of life outcomes2012

Distance saturation product predicts health-related quality of life among sarcoidosis patients.

Julie M Bourbonnais, Subramanian Malaisamy, Bhavinkumar D Dalal, Priyan C Samarakoon, Swapna R Parikh, Lobelia Samavati

Abstract read
In one paragraph

Article in Health and quality of life outcomes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Patient reported outcome measures (PROMs) in sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2017
    Review
  10. Article
  11. Development and testing of item response theory-based item banks and short forms for eye, skin and lung problems in sarcoidosis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014
    Article
  12. A conceptual model of health-related quality of life in sarcoidosis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014
    Article
  13. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Julie M BourbonnaisDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep, Wayne State University School of Medicine and Detroit Medical Center, Detroit, MI 48201, USA.
Subramanian Malaisamy
Bhavinkumar D Dalal
Priyan C Samarakoon
Swapna R Parikh
Lobelia Samavati

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcoidosis is a chronic disease with different phenotypic manifestations. Health-related quality of life is an important aspect in sarcoidosis, yet difficult to measure. The objective of this study was to identify clinical markers predictive of poor quality of life in sarcoidosis patients that can be followed over time and targeted for intervention.

methodsWe assessed the quality of life of 162 patients with confirmed sarcoidosis in a prospective, cross-sectional study using the Sarcoidosis Health Questionnaire (SHQ) and Short Form-36 Health Survey (SF-36). We evaluated the validity of these questionnaires and sought to identify variables that would best explain the performance scores of the patients.

resultsOn multivariate regression analyses, the very best composite model to predict total scores from both surveys was a model containing the distance-saturation product and Borg Dyspnea Scale score at the end of a 6-min walk test. This model could better predict SF-36 scores (R² = 0.33) than SHQ scores (R² = 0.24). Substitution of distanced walked in 6 min for the distance-saturation product in this model resulted in a lesser ability to predict both scores (R² = 0.26 for SF-36; R² = 0.22 for SHQ).

conclusionsBoth the SHQ and SF-36 surveys are valuable tools in the assessment of health-related quality of life in sarcoidosis patients. The best model to predict quality of life among these patients, as determined by regression analyses, included the distance-saturation product and Borg score after the 6-min walk test. Both variables represent easily obtainable clinical parameters that can be followed over time and targeted for intervention.

Indexed as

Surveys and QuestionnairesAdolescentAdultAgedCross-Sectional StudiesDyspneaExercise TestFatigueFemaleForced Expiratory VolumeHealth Status IndicatorsHumansMaleMichiganMiddle AgedOxygen Consumption

Identifiers

PMID22694853
PMCPMC3409072

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.