ArticlePloS one2012
Conserved expression signatures between medaka and human pigment cell tumors.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
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- Cancer Cell Biomechanical Properties Accompany Tspan8-Dependent Cutaneous Melanoma Invasion.Cancers · 2024Article
- Article
- Melanoma-Bearing Libechov Minipig (MeLiM): The Unique Swine Model of Hereditary Metastatic Melanoma.Genes · 2019Review
- Influence of Olive Extracts on the Expression of Genes Involved in Lipid Metabolism in Medaka Fish.Molecules (Basel, Switzerland) · 2019Article
- Expression Signatures of Cisplatin- and Trametinib-Treated Early-Stage Medaka Melanomas.G3 (Bethesda, Md.) · 2019Article
- Comparative Transcriptomics Between Zebrafish and Mammals: A Roadmap for Discovery of Conserved and Unique Signaling Pathways in Physiology and Disease.Frontiers in cell and developmental biology · 2019Article
- Comparison of Xiphophorus and human melanoma transcriptomes reveals conserved pathway interactions.Pigment cell & melanoma research · 2018Article
- The transcriptional response of skin to fluorescent light exposure in viviparous (Xiphophorus) and oviparous (Danio, Oryzias) fishes.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Expression signatures of early-stage and advanced medaka melanomas.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybrids.Molecular carcinogenesis · 2017Article
- Evolution of beak morphology in the Ground Tit revealed by comparative transcriptomics.Frontiers in zoology · 2017Article
- Germ cell and tumor associated piRNAs in the medaka and Xiphophorus melanoma models.BMC genomics · 2016Article
- Molecular genetic response of Xiphophorus maculatus-X. couchianus interspecies hybrid skin to UVB exposure.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
- A new model army: Emerging fish models to study the genomics of vertebrate Evo-Devo.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2015Review
- Review
- Hypoxia-independent drivers of melanoma angiogenesis.Frontiers in oncology · 2015Review
- Whole Body Melanoma Transcriptome Response in Medaka.PloS one · 2015Article
- Origins of adult pigmentation: diversity in pigment stem cell lineages and implications for pattern evolution.Pigment cell & melanoma research · 2015Review
- Beyond the zebrafish: diverse fish species for modeling human disease.Disease models & mechanisms · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aberrations in gene expression are a hallmark of cancer cells. Differential tumor-specific transcript levels of single genes or whole sets of genes may be critical for the neoplastic phenotype and important for therapeutic considerations or useful as biomarkers. As an approach to filter out such relevant expression differences from the plethora of changes noted in global expression profiling studies, we searched for changes of gene expression levels that are conserved. Transcriptomes from massive parallel sequencing of different types of melanoma from medaka were generated and compared to microarray datasets from zebrafish and human melanoma. This revealed molecular conservation at various levels between fish models and human tumors providing a useful strategy for identifying expression signatures strongly associated with disease phenotypes and uncovering new melanoma molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.