ArticleAdvances in virology2012
Epstein-barr virus as a trigger of autoimmune liver diseases.
Article in Advances in virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- Article
- Age-Dependent Hepatic Involvement in Pediatric Epstein-Barr Virus Infection: Clinical Associations and Biochemical Recovery Patterns.Journal of clinical medicine · 2026Article
- Chronic active Epstein-Barr Virus infection in a teenage girl with suspect autoimmune Hepatitis.BMC pediatrics · 2024Article
- Article
- Epstein-Barr virus induced acute hepatitis with hyperferritinemia: A rare presentation.IDCases · 2023Article
- mRNA-Based Vaccine Designing against Epstein-Barr Virus to Induce an Immune Response Using Immunoinformatic and Molecular Modelling Approaches.International journal of environmental research and public health · 2022Article
- Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report.Cureus · 2022Article
- Autoimmune Hepatitis-Challenging Diagnosis.Medicina (Kaunas, Lithuania) · 2022Article
- Trust Your Gut: The Association of Gut Microbiota and Liver Disease.Microorganisms · 2022Review
- Seronegative autoimmune hepatitis in children : A real diagnostic challenge.Wiener klinische Wochenschrift · 2022Article
- Circulating Epstein-Barr virus DNA associated with hepatic impairment and its diagnostic and prognostic role in patients with gastric cancer.Frontiers in medicine · 2022Article
- Diagnostic dilemmas in Epstein-Barr virus hepatitis mimicking autoimmune hepatitis: A case report.Journal of family medicine and primary care · 2020Article
- Acute hepatitis due to infectious mononucleosis.BMJ case reports · 2019Article
- Epstein-Barr virus infection is associated with a higher Child-Pugh score and may predict poor prognoses for patients with liver cirrhosis.BMC gastroenterology · 2019Article
- False-positive serologies for acute hepatitis A and autoimmune hepatitis in a patient with acute Epstein-Barr virus infection.BMJ case reports · 2019Article
- Pathogens and autoimmune hepatitis.Clinical and experimental immunology · 2019Review
- Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients.World journal of gastroenterology · 2018Article
- Increased Incidence of Post-transplant Lymphoproliferative Disorder in Autoimmune Liver Disease: An Irish National Experience.Journal of clinical and experimental hepatology · 2018Article
- Acute Epstein - Barr virus hepatitis without mononucleosis syndrome: a case report.Gastroenterology and hepatology from bed to bench · 2017Article
- The virus-induced HSPs regulate the apoptosis of operatus APCs that result in autoimmunity, not in homeostasis.Immunologic research · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogenesis of autoimmune diseases includes a combination of genetic factors and environmental exposures including infectious agents. Infectious triggers are commonly indicated as being involved in the induction of autoimmune disease, with Epstein-Barr virus (EBV) being implicated in several autoimmune disorders. EBV is appealing in the pathogenesis of autoimmune disease, due to its high prevalence worldwide, its persistency throughout life in the host's B lymphocytes, and its ability to alter the host's immune response and to inhibit apoptosis. However, the evidence in support of EBV in the pathogenesis varies among diseases. Autoimmune liver diseases (AiLDs), including autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC), have a potential causative link with EBV. The data surrounding EBV and AiLD are scarce. The lack of evidence surrounding EBV in AiLD may also be reflective of the rarity of these conditions. EBV infection has also been linked to other autoimmune conditions, which are often found to be concomitant with AiLD. This paper will critically examine the literature surrounding the link between EBV infection and AiLD development. The current evidence is far from being conclusive of the theory of a link between EBV and AiLD.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.