ArticleInfectious diseases in obstetrics and gynecology2012
Behavioral predictors of colonization with Lactobacillus crispatus or Lactobacillus jensenii after treatment for bacterial vaginosis: a cohort study.
Article in Infectious diseases in obstetrics and gynecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Multicenter Cross Sectional Study of the American International Biotechnology (AIBiotech) Gynecologene Test for the Evaluation of Bacterial Vaginosis/Vaginitis in Symptomatic Women
Phase 2 Placebo-controlled Randomized Trial of LACTIN-V (Lactobacillus Crispatus CTV-05) Among Women at High Risk of HIV Acquisition in Durban, South Africa
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021Guideline
- Sexually transmitted diseases treatment guidelines, 2015.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2015Guideline
- Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial.Cell host & microbe · 2026Trial
- Soluble Immune Mediators and Vaginal Bacteria Impact Innate Genital Mucosal Antimicrobial Activity in Young Women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2015Trial
- Management of Recurrent Vaginitis.Current obstetrics and gynecology reports · 2026Review
- Microbiota effects and predictors ofmedRxiv : the preprint server for health sciences · 2025Article
- Article
- Draft genome sequences of threeMicrobiology resource announcements · 2024Article
- VaginalbioRxiv : the preprint server for biology · 2023Article
- The interplay between HPV, other Sexually Transmissible Infections and genital microbiome on cervical microenvironment (MicroCervixHPV study).Frontiers in cellular and infection microbiology · 2023Observational
- Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation.Nature microbiology · 2022Article
- Reproductive tract microbiota of women in childbearing age shifts upon gynecological infections and menstrual cycle.BMC microbiology · 2021Article
- Vaginal cytokine profile and microbiota before and after lubricant use compared with condomless vaginal sex: a preliminary observational study.BMC infectious diseases · 2021Observational
- Changes to the cervicovaginal microbiota and cervical cytokine profile following surgery for cervical intraepithelial neoplasia.Scientific reports · 2021Article
- Sex Work Is Associated With Increased Vaginal Microbiome Diversity in Young Women From Mombasa, Kenya.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Draft Genome Sequence of Lactobacillus crispatus UMB1163, Isolated from the Female Urinary Tract.Microbiology resource announcements · 2020Article
- The Interaction Between Microorganisms, Metabolites, and Immune System in the Female Genital Tract Microenvironment.Frontiers in cellular and infection microbiology · 2020Review
- Personal and Clinical Vaginal Lubricants: Impact on Local Vaginal Microenvironment and Implications for Epithelial Cell Host Response and Barrier Function.The Journal of infectious diseases · 2019Article
- Lessons from Suppressive Therapy and Periodic Presumptive Treatment for Bacterial Vaginosis.Current infectious disease reports · 2019Review
- Saccharomyces cerevisiae-based probiotic as novel anti-microbial agent for therapy of bacterial vaginosis.Virulence · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveEvaluate predictors of vaginal colonization with lactobacilli after treatment for bacterial vaginosis (BV).
methodsVaginal fluid specimens from women with BV underwent qPCR for Lactobacillus crispatus, L. jensenii, and L. iners pre- and posttreatment.
resultsFew women with BV were colonized with L. crispatus (4/44, 9%) or L. jensenii (1/44, 2%), though all had L. iners. One month posttreatment 12/44 (27%) had L. crispatus, 12/44 (27%) L. jensenii, and 43/44 (98%) L. iners. Presence of L. jensenii posttreatment was associated with cure (Risk Ratio (RR) 1.67; 95% CI 1.09-2.56); L. crispatus showed a similar trend (RR 1.41; 95% CI 0.89-2.24, P = 0.14). Receptive oral sex was associated with 2.2-log(10) lower concentration of L. crispatus (95% CI -4.38, -.02), and digital-vaginal sex with 2.6-log(10) lower concentration (95% CI -4.87, -.33).
conclusionOne month after BV treatment, few women established colonization with L. crispatus or L. jensenii. Few behaviors were associated with colonization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.