ArticleThe Plant cell2012
TIME FOR COFFEE represses accumulation of the MYC2 transcription factor to provide time-of-day regulation of jasmonate signaling in Arabidopsis.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 1 of them a synthesis that pooled it.
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Who cites it
95 citing papers in PubMed, 1 synthesis or guideline pooled it, 168 citations in OpenAlex.
- Bacillus drives functional states in synthetic plant root bacterial communities.Genome biology · 2025Pooled it
- TIME FOR COFFEE coordinates phase separation and chromatin regulation for salt tolerance.Science advances · 2026Article
- Systemic acquired resistance: an emerging role for jasmonates in local signal biogenesis, translocation and distal signal decoding.The New phytologist · 2026Review
- Review
- Gene Expression Patterns Regulating Peanut Reproductive Phenology.Plant direct · 2026Article
- The core clock transcription factor TOC1 binds directly to defence gene promoters regulating immunity in Arabidopsis.Communications biology · 2026Article
- Review
- A circadian morning complex modulates far-red light signaling in Arabidopsis.Nature communications · 2025Article
- GhAOS integrates circadian rhythm and jasmonic acid signaling to regulate high temperature stress responses in cotton and Arabidopsis.BMC biology · 2025Article
- Mechanism mediating the biosynthesis of the anti-insect volatile (Z)-3-hexenyl acetate in Acacia confusa Merr., an intercropping plant in tea plantations.Molecular horticulture · 2025Article
- Alternaria alternata effector AaAlta1 targets CmWD40 and participates in regulating disease resistance in Chrysanthemum morifolium.PLoS pathogens · 2025Article
- The role of the jasmonate signalling transcription factors MYC2/3/4 in circadian clock-mediated regulation of immunity in Arabidopsis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- The overexpression of the switchgrass (Panicum virgatum L.) genes PvTOC1-N or PvLHY-K affects circadian rhythm and hormone metabolism in transgenic Arabidopsis seedlings.Biotechnology for biofuels and bioproducts · 2024Article
- A Regulatory Mechanism on Pathways: Modulating Roles of MYC2 and BBX21 in the Flavonoid Network.Plants (Basel, Switzerland) · 2024Article
- Article
- Integrated Metabolome and Transcriptome Analysis of Gibberellins Mediated the Circadian Rhythm of Leaf Elongation by Regulating Lignin Synthesis in Maize.International journal of molecular sciences · 2024Article
- The N-terminal α2 helix element is critical for the activity of the rice transcription factor MYC2.Plant molecular biology · 2024Article
- Ozone stress-induced DNA methylation variations and their transgenerational inheritance in foxtail millet.Frontiers in plant science · 2024Article
- Rose long noncoding RNA lncWD83 promotes flowering by modulating ubiquitination of the floral repressor RcMYC2L.Plant physiology · 2023Article
- The Regulatory Networks of the Circadian Clock Involved in Plant Adaptation and Crop Yield.Plants (Basel, Switzerland) · 2023Review
35 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants are confronted with predictable daily biotic and abiotic stresses that result from the day-night cycle. The circadian clock provides an anticipation mechanism to respond to these daily stress signals to increase fitness. Jasmonate (JA) is a phytohormone that mediates various growth and stress responses. Here, we found that the circadian-clock component TIME FOR COFFEE (TIC) acts as a negative factor in the JA-signaling pathway. We showed that the tic mutant is hypersensitive to growth-repressive effects of JA and displays altered JA-regulated gene expression. TIC was found to interact with MYC2, a key transcription factor of JA signaling. From this, we discovered that the circadian clock rhythmically regulates JA signaling. TIC is a key determinant in this circadian-gated process, and as a result, the tic mutant is defective in rhythmic JA responses to pathogen infection. TIC acts here by inhibiting MYC2 protein accumulation and by controlling the transcriptional repression of CORONATINE INSENSITIVE1 in an evening-phase-specific manner. Taken together, we propose that TIC acts as an output component of the circadian oscillator to influence JA signaling directly.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.