Evidence map›Paper›PMID 22692867›Full record

ArticleIEEE transactions on bio-medical engineering2012

Accelerating cardiac bidomain simulations using graphics processing units.

A Neic, M Liebmann, E Hoetzl, L Mitchell, E J Vigmond, G Haase, G Plank

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  6. Personalization of electro-mechanical models of the pressure-overloaded left ventricle: fitting of Windkessel-type afterload models.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2020
    Article
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  17. Deranged sodium to sudden death.The Journal of physiology · 2015
    Review
  18. Parallel Optimization of 3D Cardiac Electrophysiological Model Using GPU.Computational and mathematical methods in medicine · 2015
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A NeicInstitute of Mathematicsand Scientific Computing, Karl Franzens University of Graz, Graz, Austria. aurel.neic@uni-graz.at
M Liebmann
E Hoetzl
L Mitchell
E J Vigmond
G Haase
G Plank

Funding

Multi-scale Modeling of Calcium Mediated Triggered Activity in the HeartR01HL101196 · NHLBI · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI SHIFERAW, YOHANNES · 2010 to 2013
$1.2M
Austrian Science Fund FWF F 3210NHLBI NIH HHS R01 HL101196NHLBI NIH HHS R01 HL 10119601
6 · The paper itself

Abstract

Anatomically realistic and biophysically detailed multiscale computer models of the heart are playing an increasingly important role in advancing our understanding of integrated cardiac function in health and disease. Such detailed simulations, however, are computationally vastly demanding, which is a limiting factor for a wider adoption of in-silico modeling. While current trends in high-performance computing (HPC) hardware promise to alleviate this problem, exploiting the potential of such architectures remains challenging since strongly scalable algorithms are necessitated to reduce execution times. Alternatively, acceleration technologies such as graphics processing units (GPUs) are being considered. While the potential of GPUs has been demonstrated in various applications, benefits in the context of bidomain simulations where large sparse linear systems have to be solved in parallel with advanced numerical techniques are less clear. In this study, the feasibility of multi-GPU bidomain simulations is demonstrated by running strong scalability benchmarks using a state-of-the-art model of rabbit ventricles. The model is spatially discretized using the finite element methods (FEM) on fully unstructured grids. The GPU code is directly derived from a large pre-existing code, the Cardiac Arrhythmia Research Package (CARP), with very minor perturbation of the code base. Overall, bidomain simulations were sped up by a factor of 11.8 to 16.3 in benchmarks running on 6-20 GPUs compared to the same number of CPU cores. To match the fastest GPU simulation which engaged 20 GPUs, 476 CPU cores were required on a national supercomputing facility.

Indexed as

Computer GraphicsComputing MethodologiesModels, CardiovascularAlgorithmsAnimalsHeart VentriclesRabbitsVentricular Function

Identifiers

PMID22692867
PMCPMC3696513

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.