ArticleMedical care2012
A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data.
Article in Medical care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
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- Fueling Clinical and Translational Research in Appalachia: Informatics Platform Approach.JMIR medical informatics · 2020Article
- A conceptual framework for evaluating data suitability for observational studies.Journal of the American Medical Informatics Association : JAMIA · 2018Article
- Pragmatic (trial) informatics: a perspective from the NIH Health Care Systems Research Collaboratory.Journal of the American Medical Informatics Association : JAMIA · 2017Article
- A Framework for Classification of Electronic Health Data Extraction-Transformation-Loading Challenges in Data Network Participation.EGEMS (Washington, DC) · 2017Article
- Clinical Research Informatics for Big Data and Precision Medicine.Yearbook of medical informatics · 2016Article
- Clinical Decision Support: a 25 Year Retrospective and a 25 Year Vision.Yearbook of medical informatics · 2016Review
- 'Big data' in mental health research: current status and emerging possibilities.Social psychiatry and psychiatric epidemiology · 2016Review
- Facilitating biomedical researchers' interrogation of electronic health record data: Ideas from outside of biomedical informatics.Journal of biomedical informatics · 2016Review
- Extracting Electronic Health Record Data in a Practice-Based Research Network: Processes to Support Translational Research across Diverse Practice Organizations.EGEMS (Washington, DC) · 2016Article
- Software-Enabled Distributed Network Governance: The PopMedNet Experience.EGEMS (Washington, DC) · 2016Article
- A Multiagent System for Dynamic Data Aggregation in Medical Research.BioMed research international · 2016Article
- Research Data Explorer: Lessons Learned in Design and Development of Context-based Cohort Definition and Selection.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2015Article
- The HMO Research Network Virtual Data Warehouse: A Public Data Model to Support Collaboration.EGEMS (Washington, DC) · 2014Article
- Achieving and sustaining automated health data linkages for learning systems: barriers and solutions.EGEMS (Washington, DC) · 2014Article
- The Community Health Applied Research Network (CHARN) Data Warehouse: a Resource for Patient-Centered Outcomes Research and Quality Improvement in Underserved, Safety Net Populations.EGEMS (Washington, DC) · 2014Article
- Sustaining Research Networks: the Twenty-Year Experience of the HMO Research Network.EGEMS (Washington, DC) · 2014Article
- Improving quality and safety of care using "technovigilance": an ethnographic case study of secondary use of data from an electronic prescribing and decision support system.The Milbank quarterly · 2013Article
- Knowledge management and informatics considerations for comparative effectiveness research: a case-driven exploration.Medical care · 2013Article
- Practice-Based Knowledge Discovery for Comparative Effectiveness Research: An Organizing Framework.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2013Article
Corrections and comments
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Authors and funding
7 authors at 7 institutions in 1 country.
Funding
Abstract
Comparative effectiveness research (CER) has the potential to transform the current health care delivery system by identifying the most effective medical and surgical treatments, diagnostic tests, disease prevention methods, and ways to deliver care for specific clinical conditions. To be successful, such research requires the identification, capture, aggregation, integration, and analysis of disparate data sources held by different institutions with diverse representations of the relevant clinical events. In an effort to address these diverse demands, there have been multiple new designs and implementations of informatics platforms that provide access to electronic clinical data and the governance infrastructure required for interinstitutional CER. The goal of this manuscript is to help investigators understand why these informatics platforms are required and to compare and contrast 6 large-scale, recently funded, CER-focused informatics platform development efforts. We utilized an 8-dimension, sociotechnical model of health information technology to help guide our work. We identified 6 generic steps that are necessary in any distributed, multi-institutional CER project: data identification, extraction, modeling, aggregation, analysis, and dissemination. We expect that over the next several years these projects will provide answers to many important, and heretofore unanswerable, clinical research questions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.