ArticleThe Journal of biological chemistry2012
Molecular interactions of GBF1 with HY5 and HYH proteins during light-mediated seedling development in Arabidopsis thaliana.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48 citing papers in PubMed, 99 citations in OpenAlex.
- Functional Characterisation of NF-YCs in True Leaf Biomass Accumulation.Plants (Basel, Switzerland) · 2026Article
- Light interacts with mechanical stress to regulate the seed-to-seedling transition.Stress biology · 2025Review
- BnaC04.bZIP16 can be phosphorylated and inhibited by BnaA06.SnRK2 and negatively regulates the accumulation of fatty acids in Brassica napus.The Plant journal : for cell and molecular biology · 2025Article
- Genome-wide identification and functional analysis of PEL gene family in Brassica napus L.BMC plant biology · 2025Article
- Requirement of two simultaneous environmental signals for activation of ArabidopsisPlant signaling & behavior · 2024Article
- Ubiquitin-specific protease UBP14 stabilizes HY5 by deubiquitination to promote photomorphogenesis inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Genome-wide analysis of the bZIP gene family inHeliyon · 2024Article
- An interplay between bZIP16, bZIP68, and GBF1 regulates nuclear photosynthetic genes during photomorphogenesis in Arabidopsis.The New phytologist · 2023Article
- Review
- Translational activation of ribosome-related genes at initial photoreception is dependent on signals derived from both the nucleus and the chloroplasts in Arabidopsis thaliana.Journal of plant research · 2023Article
- Genome-Wide Identification, Classification, Expression and Duplication Analysis of bZIP Family Genes inInternational journal of molecular sciences · 2022Article
- How plants protect themselves from ultraviolet-B radiation stress.Plant physiology · 2021Review
- Calmodulin7: recent insights into emerging roles in plant development and stress.Plant molecular biology · 2021Review
- HY5 and ABI5 transcription factors physically interact to fine tune light and ABA signaling in Arabidopsis.Plant molecular biology · 2021Article
- Meeting at the DNA: Specifying Cytokinin Responses through Transcription Factor Complex Formation.Plants (Basel, Switzerland) · 2021Review
- COR27 and COR28 Are Novel Regulators of the COP1-HY5 Regulatory Hub and Photomorphogenesis in Arabidopsis.The Plant cell · 2020Article
- Chimeric Activators and Repressors Define HY5 Activity and Reveal a Light-Regulated Feedback Mechanism.The Plant cell · 2020Article
- Modulation of BIN2 kinase activity by HY5 controls hypocotyl elongation in the light.Nature communications · 2020Article
- Time-Course Transcriptome Study Reveals Mode of bZIP Transcription Factors on Light Exposure inInternational journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arabidopsis bZIP transcription factor, GBF1, acts as a differential regulator of cryptochrome-mediated blue light signaling. Whereas the bZIP proteins, HY5 (elongated hypocotyl 5) and HYH (HY5 homologue), are degraded by COP1-mediated proteasomal pathways, GBF1 is degraded by a proteasomal pathway independent of COP1. In this study, we have investigated the functional interrelations of GBF1 with HY5 and HYH in Arabidopsis seedling development. The genetic studies using double and triple mutants reveal that GBF1 largely acts antagonistically with HY5 and HYH in Arabidopsis seedling development. Further, GBF1 and HY5 play more important roles than HYH in blue light-mediated photomorphogenic growth. This study reveals that GBF1 is able to form a G-box-binding heterodimer with HY5 but not with HYH. The in vitro and in vivo studies demonstrate that GBF1 co-localizes with HY5 or HYH in the nucleus and physically interacts with both of the proteins. The protein-protein interaction studies further reveal that the bZIP domain of GBF1 is essential and sufficient for the interaction with HY5 or HYH. Taken together, these data demonstrate the functional interrelations of GBF1 with HY5 and HYH in Arabidopsis seedling development.
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