Evidence map›Paper›PMID 22691267›Full record

ArticleGenomics2012

ERE database: a database of genomic maps and biological properties of endogenous retroviral elements in the C57BL/6J mouse genome.

Damian Kao, Karen Hsu, Sophia Chiu, Vince Tu, Alex Chew, Kang-Hoon Lee, Young-Kwan Lee, Deug-Nam Kwon, David G Greenhalgh, Kiho Cho

Abstract read
In one paragraph

Article in Genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Damian KaoBurn Research, Shriners Hospitals for Children Northern California, Sacramento, CA 95817, USA.
Karen Hsu
Sophia Chiu
Vince Tu
Alex Chew
Kang-Hoon Lee
Young-Kwan Lee
Deug-Nam Kwon
David G Greenhalgh
Kiho Cho
Shriners Hospitals for Children - Erie · US

Funding

Endogenous Retroviruses and Gene Regulation After InjuryR01GM071360 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHO, KIHO · 2006 to 2010
$1.1M
NIGMS NIH HHS R01 GM071360NIGMS NIH HHS R01GM071360
6 · The paper itself

Abstract

Endogenous retroviral elements (EREs), a family of transposable elements, constitute a substantial fraction of mammalian genomes. It is expected that profiles of the ERE sequences and their genomic locations are unique for each individual. Comprehensive characterization of the EREs' genomic locations and their biological properties is essential for understanding their roles in the pathophysiology of the host. In this study, we identified and mapped putative EREs (a total of 111 endogenous retroviruses [ERVs] and 488 solo long terminal repeats [sLTRs]) within the C57BL/6J mouse genome. The biological properties of individual ERE isolates (both ERVs and sLTRs) were then characterized in the following aspects: transcription potential, tropism trait, coding potential, recombination event, integration age, and primer binding site for replication. In addition, a suite of database management system programs was developed to organize and update the data acquired from current and future studies and to make the data accessible via internet.

Indexed as

Databases, GeneticGenomeSoftwareAnimalsBinding SitesChromosome MappingDNA PrimersEndogenous RetrovirusesMiceMice, Inbred C57BLOpen Reading FramesPhylogenyPromoter Regions, GeneticRecombination, GeneticRegulatory Elements, TranscriptionalSequence Analysis, DNADNA Primers

Identifiers

PMID22691267
PMCPMC3428438
OpenAlexW2022960076

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.