ArticleBMC evolutionary biology2012
Ancient gene transfer from algae to animals: mechanisms and evolutionary significance.
Article in BMC evolutionary biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Genome-Wide Comparative and Phylogenetic Analysis of Putative Algal Carbohydrate Sulfotransferases.Journal of molecular evolution · 2026Article
- Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1.Frontiers in physiology · 2022Article
- Perspectives and potential applications of endophytic microorganisms in cultivation of medicinal and aromatic plants.Frontiers in plant science · 2022Review
- Chlamydomonas proteases: classification, phylogeny, and molecular mechanisms.Journal of experimental botany · 2021Article
- Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava).Molecular ecology resources · 2020Article
- Alienness: Rapid Detection of Candidate Horizontal Gene Transfers across the Tree of Life.Genes · 2017Article
- Horizontal functional gene transfer from bacteria to fishes.Scientific reports · 2015Article
- Article
- An overview of malaria transmission from the perspective of Amazon Anopheles vectors.Memorias do Instituto Oswaldo Cruz · 2015Review
- Ancient interaction between the teneurin C-terminal associated peptides (TCAP) and latrophilin ligand-receptor coupling: a role in behavior.Frontiers in neuroscience · 2015Review
- Metagenomics, paratransgenesis and the Anopheles microbiome: a portrait of the geographical distribution of the anopheline microbiota based on a meta-analysis of reported taxa.Memorias do Instituto Oswaldo Cruz · 2014Review
- An ancient relative of cyclooxygenase in cyanobacteria is a linoleate 10S-dioxygenase that works in tandem with a catalase-related protein with specific 10S-hydroperoxide lyase activity.The Journal of biological chemistry · 2014Article
- Root parasitic plant Orobanche aegyptiaca and shoot parasitic plant Cuscuta australis obtained Brassicaceae-specific strictosidine synthase-like genes by horizontal gene transfer.BMC plant biology · 2014Article
- The scale and evolutionary significance of horizontal gene transfer in the choanoflagellate Monosiga brevicollis.BMC genomics · 2013Article
- How protein targeting to primary plastids via the endomembrane system could have evolved? A new hypothesis based on phylogenetic studies.Biology direct · 2013Article
- Evolution of land plant genes encoding L-Ala-D/L-Glu epimerases (AEEs) via horizontal gene transfer and positive selection.BMC plant biology · 2013Article
- Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes.Genome biology · 2013Article
- Algal genes in aplastidic eukaryotes are not necessarily derived from historical plastids.Mobile genetic elements · 2012Article
- Widespread impact of horizontal gene transfer on plant colonization of land.Nature communications · 2012Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHorizontal gene transfer (HGT) is traditionally considered to be rare in multicellular eukaryotes such as animals. Recently, many genes of miscellaneous algal origins were discovered in choanoflagellates. Considering that choanoflagellates are the existing closest relatives of animals, we speculated that ancient HGT might have occurred in the unicellular ancestor of animals and affected the long-term evolution of animals.
resultsThrough genome screening, phylogenetic and domain analyses, we identified 14 gene families, including 92 genes, in the tunicate Ciona intestinalis that are likely derived from miscellaneous photosynthetic eukaryotes. Almost all of these gene families are distributed in diverse animals, suggesting that they were mostly acquired by the common ancestor of animals. Their miscellaneous origins also suggest that these genes are not derived from a particular algal endosymbiont. In addition, most genes identified in our analyses are functionally related to molecule transport, cellular regulation and methylation signaling, suggesting that the acquisition of these genes might have facilitated the intercellular communication in the ancestral animal.
conclusionsOur findings provide additional evidence that algal genes in aplastidic eukaryotes are not exclusively derived from historical plastids and thus important for interpreting the evolution of eukaryotic photosynthesis. Most importantly, our data represent the first evidence that more anciently acquired genes might exist in animals and that ancient HGT events have played an important role in animal evolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.