ArticleInternational journal of environmental research and public health2012
Can we modify the intrauterine environment to halt the intergenerational cycle of obesity?
Article in International journal of environmental research and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- The Effectiveness of eHealth Technologies on Weight Management in Pregnant and Postpartum Women: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2017Pooled it
- Pooled it
- Lifestyle intervention before and during fertility treatment in women with obesity or with overweight and PCOS-a RCT.The Journal of clinical endocrinology and metabolism · 2026Trial
- Uncontrolled Eating during Pregnancy Predicts Fetal Growth: The Healthy Mom Zone Trial.Nutrients · 2019Trial
- Breastfeeding initiation: impact of obesity in a large Canadian perinatal cohort study.PloS one · 2015Trial
- Antenatal exercise in overweight and obese women and its effects on offspring and maternal health: design and rationale of the IMPROVE (Improving Maternal and Progeny Obesity Via Exercise) randomised controlled trial.BMC pregnancy and childbirth · 2014Trial
- Healthy living in pregnancy: a cluster-randomized controlled trial to prevent excessive gestational weight gain - rationale and design of the GeliS study.BMC pregnancy and childbirth · 2014Trial
- Safety and efficacy of a lifestyle intervention for pregnant women to prevent excessive maternal weight gain: a cluster-randomized controlled trial.BMC pregnancy and childbirth · 2013Trial
- Physically active pregnancies: Insights from the placenta.Physiological reports · 2024Review
- Exploring Lifestyle and Dietary Patterns in Pregnancy and Their Impact on Health: A Comparative Analysis of Two Distinct Groups 10 Years Apart.Nutrients · 2024Article
- Excessive Gestational Weight Gain and Pregnancy Outcomes.Journal of clinical medicine · 2023Article
- Impact of BMI and smoking in adolescence and at the start of pregnancy on birth weight.BMC pregnancy and childbirth · 2023Article
- Fetal programming of obesity and type 2 diabetes.World journal of diabetes · 2022Review
- Sex Differences Across the Life Course: A Focus On Unique Nutritional and Health Considerations among Women.The Journal of nutrition · 2022Article
- Article
- Time to Consider the "Exposome Hypothesis" in the Development of the Obesity Pandemic.Nutrients · 2022Review
- Article
- Association of Maternal Prepregnancy Weight and Gestational Weight Gain With Children's Allergic Diseases.JAMA network open · 2020Article
- Serum Microelements in Early Pregnancy and their Risk of Large-for-Gestational Age Birth Weight.Nutrients · 2020Article
- Efficacy and safety of combination of magnesium sulfate, phentolamine and nifedipine in treatment of patients with hypertensive disorder complicating pregnancy.Experimental and therapeutic medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Child obesity is a global epidemic whose development is rooted in complex and multi-factorial interactions. Once established, obesity is difficult to reverse and epidemiological, animal model, and experimental studies have provided strong evidence implicating the intrauterine environment in downstream obesity. This review focuses on the interplay between maternal obesity, gestational weight gain and lifestyle behaviours, which may act independently or in combination, to perpetuate the intergenerational cycle of obesity. The gestational period, is a crucial time of growth, development and physiological change in mother and child. This provides a window of opportunity for intervention via maternal nutrition and/or physical activity that may induce beneficial physiological alternations in the fetus that are mediated through favourable adaptations to in utero environmental stimuli. Evidence in the emerging field of epigenetics suggests that chronic, sub-clinical perturbations during pregnancy may affect fetal phenotype and long-term human data from ongoing randomized controlled trials will further aid in establishing the science behind ones predisposition to positive energy balance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.