ArticleInternational journal of environmental research and public health2012
Assessment of exposure to alcohol vapor from alcohol-based hand rubs.
Article in International journal of environmental research and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Inhalation of Alcohol Vapor: Measurement and Implications.Alcoholism, clinical and experimental research · 2017Pooled it
- Contribution of dermal ethanol absorption during laboratory-controlled high-frequency use of alcohol-based hand rubs followed by glove use.Archives of toxicology · 2026Article
- Ethanol Inhalation for Respiratory Infections due to Enveloped Viruses.Infectious diseases and therapy · 2025Review
- Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options.Pharmacology, biochemistry, and behavior · 2024Review
- Increasing Optical Path Lengths in Micro-Fluidic Devices Using a Multi-Pass Cell.Micromachines · 2024Article
- A phase I clinical trial assessing the safety, tolerability, and pharmacokinetics of inhaled ethanol in humans as a potential treatment for respiratory tract infections.Frontiers in medicine · 2024Article
- Volatile organic compounds and ionic substances contamination in cell processing facilities during rest period; a preliminary assessment of exposure to cell processing operators.Regenerative therapy · 2023Article
- Handheld device quantifies breath acetone for real-life metabolic health monitoring.Sensors & diagnostics · 2023Article
- Positive Correlation Between Heavy Alcoholic Drinking and SARS-Cov-2 Non-Infection Rate.Cureus · 2023Article
- Ethanol and NaCl-Induced Gold Nanoparticle Aggregation Toxicity toward DNA Investigated with a DNA/GCE Biosensor.Sensors (Basel, Switzerland) · 2023Article
- Environmental formaldehyde sensing at room temperature by smartphone-assisted and wearable plasmonic nanohybrids.Nanoscale · 2023Article
- Assessment of ethanol exposure from hand sanitizer use and potential for developmental toxicity in nursing infants.Journal of applied toxicology : JAT · 2022Review
- Room-Temperature Catalyst Enables Selective Acetone Sensing.Materials (Basel, Switzerland) · 2021Article
- Monitoring Lipolysis by Sensing Breath Acetone down to Parts-per-Billion.Small science · 2021Article
- Development and Characterization of Inhaled Ethanol as a Novel Pharmacological Strategy Currently Evaluated in a Phase II Clinical Trial for Early-Stage SARS-CoV-2 Infection.Pharmaceutics · 2021Article
- The rationale of ethanol inhalation for disinfection of the respiratory tract in SARS-CoV-2-positive asymptomatic subjects.The Pan African medical journal · 2021Article
- Superior Acetone Selectivity in Gas Mixtures by Catalyst-Filtered Chemoresistive Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Sanitizer aerosol-driven ocular surface disease (SADOSD)-A COVID-19 repercussion?Indian journal of ophthalmology · 2020Article
- Rapid and Selective NHAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Peak Inhalation Exposure Metrics Used in Occupational Epidemiologic and Exposure Studies.Frontiers in public health · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study assessed the inhaled dose of alcohol during hand disinfection. Experiments were conducted with two types of hand rub using two hand disinfection procedures. Air samples were collected every 10 s from the breathing zone, by bubbling through a mixture of K(2)Cr(2)O(7) and H(2)SO(4). The reduction of dichromate ions in the presence of alcohols was followed by UV-vis spectrophotometry. The difference in intensity of the dichromate absorption peak was used to quantify the alcohol concentration expressed in ethanol equivalent. During hygienic hand disinfection, the mean ethanol equivalent concentrations peaked at around 20-30 s for both hand rubs (14.3 ± 1.4 mg/L for hand rub 1 and 13.2 ± 0.7 mg/L for hand rub 2). During surgical hand disinfection, two peaks were found at the same time (40 and 80 s) for both hand rubs. The highest mean concentrations were 20.2 ± 0.9 mg/L for hand rub 1 and 18.1 ± 0.9 mg/L for hand rub 2. For hand rub 1, the total absorbed doses, calculated from ethanol with an inhalation flow of 24 L/min and an absorption rate of 62%, were 46.5 mg after one hygienic hand disinfection and 203.9 mg after one surgical hand disinfection. Although the use of ABHRs leads to the absorption of very low doses, sudden, repeated inhalation of high alcohol concentrations raises the question of possible adverse health effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.