Evidence map›Paper›PMID 22688862›Full record

ArticleCurrent osteoporosis reports2012

Fracture risk assessment: state of the art, methodologically unsound, or poorly reported?

Gary S Collins, Karl Michaëlsson

Abstract read
PubMed Publisher
In one paragraph

Article in Current osteoporosis reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Review
  4. Review
  5. Predictive analytics in health care: how can we know it works?Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Osteoporosis: the emperor has no clothes.Journal of internal medicine · 2015
    Review
  12. Fragility fracture: recent developments in risk assessment.Therapeutic advances in musculoskeletal disease · 2015
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Osteoporosis and fracture risk in older people.Clinical medicine (London, England) · 2014
    Article
  18. Conflicts at the heart of the FRAX tool.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gary S CollinsCentre for Statistics in Medicine, Wolfson College Annexe, University of Oxford, Linton Road, Oxford OX2 6UD, UK. gary.collins@csm.ox.ac.uk
Karl Michaëlsson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporotic fractures, including hip fractures, are a global health concern associated with significant morbidity and mortality as well as a major economic burden. Identifying individuals who are at an increased risk of osteoporotic fracture is an important challenge to be resolved. Recently, multivariable prediction tools have been developed to assist clinicians in the management of their patients by calculating their 10-year risk of fracture (FRAX, QFracture, Garvan) using a combination of known risk factors. These prediction models have revolutionized the way clinicians assess the risk of fracture. Studies evaluating the performance of prediction models in this and other areas of medicine have, however, been characterized by poor design, methodological conduct, and reporting. We examine recently developed fracture prediction models and critically discuss issues in their design, validation, and transparency.

Indexed as

Osteoporotic FracturesHip FracturesHumansPrognosisReview Literature as TopicRisk AssessmentRisk FactorsValidation Studies as Topic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.