Evidence map›Paper›PMID 22688429›Full record

Trial reportArchives of ophthalmology (Chicago, Ill. : 1960)2012

Impact of a health communication intervention to improve glaucoma treatment adherence. Results of the interactive study to increase glaucoma adherence to treatment trial.

Karen Glanz, Allen D Beck, Lucja Bundy, Susan Primo, Michael J Lynn, Julia Cleveland, Jessica A Wold, Katharina V Echt

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of ophthalmology (Chicago, Ill. : 1960), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00794170 (I-SIGHT), which is not on this map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00794170 nacompletednot on this map

I-SIGHT: Interactive Study to Increase Glaucoma adHerence to Treatment Phase 2: Participant Recruitment & Intervention Delivery and Evaluation

TypeinterventionalSponsorEmory UniversityRan2008 to 2010Enrolled312ConditionsGlaucomaArmsTelephone and Print based intervention
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Interventions for improving adherence to ocular hypotensive therapy.The Cochrane database of systematic reviews · 2013
    Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Observational
  13. A novel EyePhone© App for improving adherence to glaucoma therapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Glaucoma medication adherence among African Americans: program development.Optometry and vision science : official publication of the American Academy of Optometry · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karen GlanzPerelman School of Medicine and School of Nursing, University of Pennsylvania, Philadelphia, USA.
Allen D Beck
Lucja Bundy
Susan Primo
Michael J Lynn
Julia Cleveland
Jessica A Wold
Katharina V Echt

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI NICKERSON, JOHN M · 1986 to 2025
$15.3M
Telephone E-Health Communication for Improving Glaucoma Treatment ComplianceR01EY016997 · NEI · UNIVERSITY OF PENNSYLVANIA · PI GLANZ, KAREN · 2006 to 2009
$1.4M
NEI NIH HHS P30 EY 006360NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY016997
6 · The paper itself

Abstract

objectiveTo determine the efficacy of an automated, interactive, telephone-based health communication intervention for improving glaucoma treatment adherence among patients in 2 hospital-based eye clinics.

methodA total of 312 patients with glaucoma (18-80 years of age) were enrolled in a randomized controlled trial at 2 eye clinics located in hospitals in the southeastern United States. These patients were considered nonadherent because they did not take their medication, refill their medication, and/or keep their appointments. The treatment group received an automated, interactive, tailored, telephone-based health communication intervention and tailored print materials. The control group received usual care.

main outcome measuresAdherence with medication taking, prescription refills, and appointment keeping measured by interviews, medical charts, appointment records, and pharmacy data.

resultsA statistically significant increase was found for all adherence measures in both the intervention and control groups. Interactive telephone calls and tailored print materials did not significantly improve adherence measures compared with controls.

conclusionsDuring the study period, patient adherence to glaucoma treatment and appointment keeping improved in both study arms. Participation in the study and interviews may have contributed. Strategies that address individuals' barriers and facilitators may increase the impact of telephone calls, especially for appointment keeping and prescription refills. APPLICATION TO CLINICAL PRACTICE: Glaucoma patient care should include reminders about consistent use of medication and the importance of keeping appointments. More frequent, and personalized, telephone contact may be helpful to patients who are known to be nonadherent.

trial registrationclinicaltrials.gov Identifier:NCT00794170.

Indexed as

Medication AdherencePatient Education as TopicAdolescentAdultAgedAged, 80 and overAntihypertensive AgentsAppointments and SchedulesDrug PrescriptionsFemaleGlaucomaHealth BehaviorHealth CommunicationHealth PromotionHumansMaleAntihypertensive AgentsOphthalmic Solutions

Identifiers

PMID22688429
PMCPMC3593648

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.