ArticleMolecular psychiatry2012
Visual analysis of geocoded twin data puts nature and nurture on the map.
Article in Molecular psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Mapping associations of polygenic scores with autistic and ADHD traits in a single city region.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Where you live matters: visualizing environmental effects on reading attainment.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- Child effects on positive parenting vary with neighborhood opportunity.Developmental psychology · 2024Article
- The social determinants of mental health and disorder: evidence, prevention and recommendations.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Mapping the genetic and environmental aetiology of autistic traits in Sweden and the United Kingdom.JCPP advances · 2021Article
- Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia.Nature communications · 2018Article
- Gene-obesogenic environment interactions in the UK Biobank study.International journal of epidemiology · 2017Article
- THE ROLE OF PHYSICAL CAPITAL ASSETS IN YOUNG GIRLS' AND BOYS' MORTALITY AND GROWTH IN LOW- AND MIDDLE-INCOME COUNTRIES.Monographs of the Society for Research in Child Development · 2016Article
- Stability and Change in Genetic and Environmental Influences on Well-Being in Response to an Intervention.PloS one · 2016Article
- From observational to dynamic genetics.Frontiers in genetics · 2014Article
- Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Twin studies allow us to estimate the relative contributions of nature and nurture to human phenotypes by comparing the resemblance of identical and fraternal twins. Variation in complex traits is a balance of genetic and environmental influences; these influences are typically estimated at a population level. However, what if the balance of nature and nurture varies depending on where we grow up? Here we use statistical and visual analysis of geocoded data from over 6700 families to show that genetic and environmental contributions to 45 childhood cognitive and behavioral phenotypes vary geographically in the United Kingdom. This has implications for detecting environmental exposures that may interact with the genetic influences on complex traits, and for the statistical power of samples recruited for genetic association studies. More broadly, our experience demonstrates the potential for collaborative exploratory visualization to act as a lingua franca for large-scale interdisciplinary research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.