Evidence map›Paper›PMID 22687239›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2012

Depression management in primary care: an observational study of management changes related to PHQ-9 score for depression monitoring.

Michael Moore, Saima Ali, Beth Stuart, Gerry M Leydon, Jessica Ovens, Chris Goodall, Tony Kendrick

Abstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Assessing depression severity using the UK Quality and Outcomes Framework depression indicators: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
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  14. The Changes of Psychometric Profiles after Medical Treatment of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2015
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  15. Use of PHQ-9 scores to guide treatment decisions in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Article
  16. Improving the reporting and interpretation of clinical trial outcomes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael MoorePrimary and Population Science, University of Southampton, Southampton, UK. mvm198@soton.ac.uk
Saima Ali
Beth Stuart
Gerry M Leydon
Jessica Ovens
Chris Goodall
Tony Kendrick

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince 2009 UK GPs have been incentivised to use depression severity scores to monitor patients' response to treatment after 5-12 weeks of treatment.

aimTo examine the association between the severity scores obtained and follow-up questionnaires to monitor depression and subsequent changes made to the treatment of it. DESIGN AND

settingA retrospective cohort study utilising routine primary care records was conducted between April 2009 and March 2011 in 13 general practices recruited from within Hampshire, Wiltshire, and Southampton City primary care trusts.

methodRecords were examined of 604 patients who had received a new diagnosis of depression since 1 April 2009, and who had completed the nine-item depression scale of the Patient Health Questionnaire (PHQ-9) at initial diagnosis and a subsequent PHQ-9 within 6 months. The main outcome measure was the odds ratio (OR) for a change in depression management. Change in management was defined as change in antidepressant drug prescription, dose, or referral.

resultsControlling for the effects of potentially confounding factors, patients who showed an inadequate response in score change at the time of second assessment were nearly five times as likely to experience a subsequent change to treatment in comparison with those who showed an adequate response (OR 4.72, 95% confidence interval = 2.83 to 7.86).

conclusionGPs' decisions to change treatment or to make referrals following a second PHQ-9 appear to be in line with guidance from the National Institute for Health and Clinical Excellence for the monitoring of depression in primary care. Although the present study demonstrates an association between a lack of change in questionnaire scores and treatment changes, the extent to which scores influence choice and whether they are associated with improvements in depression outcomes is an important area for further research.

Indexed as

AdultAntidepressive AgentsDepressive DisorderEnglandFemaleGeneral PracticeHumansMalePractice Patterns, Physicians'Psychiatric Status Rating ScalesReferral and ConsultationRetrospective StudiesTreatment OutcomeAntidepressive Agents

Identifiers

PMID22687239
PMCPMC3361126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.