Evidence map›Paper›PMID 22687140›Full record

Observational studyCritical care (London, England)2012

Impact of whole-body computed tomography on mortality and surgical management of severe blunt trauma.

Jean-Michel Yeguiayan, Anabelle Yap, Marc Freysz, Delphine Garrigue, Claude Jacquot, Claude Martin, Christine Binquet, Bruno Riou, Claire Bonithon-Kopp, FIRST Study Group

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Critical care (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04937868 (Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients), which is not on this map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04937868 recruitingnot on this mapstarted 2018, after this paper: background citation

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

TypeobservationalSponsorUniversity of California, Los AngelesRan2018 to 2027Enrolled12,000ConditionsAbdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine InjuryArmsThere are no interventions associated with this study
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Observational
  7. Article
  8. Article
  9. Lessons learned during the sliding gantry CT implementation in a trauma suite.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  10. Article
  11. Article
  12. Observational
  13. The impact of a qualified medical documentation assistant on trauma room management.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  14. Observational
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jean-Michel Yeguiayan
Anabelle Yap
Marc Freysz
Delphine Garrigue
Claude Jacquot
Claude Martin
Christine Binquet
Bruno Riou
Claire Bonithon-Kopp
FIRST Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe mortality benefit of whole-body computed tomography (CT) in early trauma management remains controversial and poorly understood. The objective of this study was to assess the impact of whole-body CT compared with selective CT on mortality and management of patients with severe blunt trauma.

methodsThe FIRST (French Intensive care Recorded in Severe Trauma) study is a multicenter cohort study on consecutive patients with severe blunt trauma requiring admission to intensive care units from university hospital trauma centers within the first 72 hours. Initial data were combined to construct a propensity score to receive whole-body CT and selective CT used in multivariable logistic regression models, and to calculate the probability of survival according to the Trauma and Injury Severity Score (TRISS) for 1,950 patients. The main endpoint was 30-day mortality.

resultsIn total, 1,696 patients out of 1,950 (87%) were given whole-body CT. The crude 30-day mortality rates were 16% among whole-body CT patients and 22% among selective CT patients (p = 0.02). A significant reduction in the mortality risk was observed among whole-body CT patients whatever the adjustment method (OR = 0.58, 95% CI: 0.34-0.99 after adjustment for baseline characteristics and post-CT treatment). Compared to the TRISS predicted survival, survival significantly improved for whole-body CT patients but not for selective CT patients. The pattern of early surgical and medical procedures significantly differed between the two groups.

conclusionsDiagnostic whole-body CT was associated with a significant reduction in 30-day mortality among patients with severe blunt trauma. Its use may be a global indicator of better management.

Indexed as

Disease ManagementTrauma Severity IndicesAdultCohort StudiesFemaleHumansMaleMiddle AgedMortalityProspective StudiesTomography, X-Ray ComputedWounds, NonpenetratingYoung Adult

Identifiers

PMID22687140
PMCPMC3580653

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.