ArticleInternational journal of rheumatology2012
Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO).
Article in International journal of rheumatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Response of Different Treatment Protocols to Treat Chronic Non-Bacterial Osteomyelitis (CNO) of the Mandible in Adult Patients: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Autoinflammatory Bone Diseases.Balkan medical journal · 2025Review
- Vertebra Plana: A Narrative Clinical and Imaging Overview among Possible Differential Diagnoses.Diagnostics (Basel, Switzerland) · 2023Review
- New insights on multigenic autoinflammatory diseases.Therapeutic advances in musculoskeletal disease · 2022Review
- Chronic Nonbacterial Osteomyelitis in Children.Children (Basel, Switzerland) · 2021Review
- Chronic nonbacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO).Journal of translational autoimmunity · 2021Review
- The molecular pathophysiology of chronic non-bacterial osteomyelitis (CNO)-a systematic review.Molecular and cellular pediatrics · 2017Review
- Periodontal and other oral manifestations of immunodeficiency diseases.Oral diseases · 2017Review
- Adult-onset Chronic Recurrent Multifocal Osteomyelitis with High Intensity of Muscles Detected by Magnetic Resonance Imaging, Successfully Controlled with Tocilizumab.Internal medicine (Tokyo, Japan) · 2017Article
- Bone metabolism and inflammatory characteristics in 14 cases of chronic nonbacterial osteomyelitis.Pediatric rheumatology online journal · 2017Article
- Whole-body MRI in patients with Non-bacterial Osteitis: Radiological findings and correlation with clinical data.European radiology · 2017Article
- Successful treatment of chronic recurrent multifocal osteomyelitis using low-dose radiotherapy : A case report.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2017Article
- Serum Interleukin-6 and CCL11/Eotaxin May Be Suitable Biomarkers for the Diagnosis of Chronic Nonbacterial Osteomyelitis.Frontiers in pediatrics · 2017Article
- Chronic nonbacterial osteomyelitis involving the mandible: A case report.International journal of surgery case reports · 2017Article
- Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO).Rheumatology international · 2016Article
- Whole-body MRI: non-oncological applications in paediatrics.La Radiologia medica · 2016Review
- New discoveries in CRMO: IL-1β, the neutrophil, and the microbiome implicated in disease pathogenesis in Pstpip2-deficient mice.Seminars in immunopathology · 2015Review
- Nonbacterial osteitis of the clavicle: longitudinal imaging series from initial diagnosis to clinical improvement.Case reports in rheumatology · 2015Article
- Syndromes with chronic non-bacterial osteomyelitis in the spine.Reumatologia · 2015Article
- Primary Chronic Osteomyelitis of the Jaws in Children: An Update on Pathophysiology, Radiological Findings, Treatment Strategies, and Prospective Analysis of Two Cases.Case reports in dentistry · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic nonbacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO) is a non-bacterial osteitis of yet unknown origin. Secondary to the absence of both high-titer autoantibodies and autoreactive T lymphocytes, and the association with other autoimmune diseases, it was recently reclassified as an autoinflammatory disorder of the musculoskeletal system. Since its etiology is largely unknown, the diagnosis is based on clinical criteria, and treatment is empiric and not always successful. In this paper, we summarize recent advances in the understanding of possible etiopathogenetic mechanisms in CNO.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.