ArticleFrontiers in physiology2012
Arsenic toxicity: the effects on plant metabolism.
Article in Frontiers in physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers.
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Who cites it
164 citing papers in PubMed, 824 citations in OpenAlex.
- Trehalose: a potent enhancer of antioxidant responses inPlant signaling & behavior · 2026Article
- Exogenous kinetin mitigates arsenic-induced oxidative stress by regulating ROS homeostasis and antioxidant defense in Ocimum basilicum L.Plant cell reports · 2026Article
- Superionic Germanium Substituted Lithium Thioarsante LiSmall (Weinheim an der Bergstrasse, Germany) · 2026Article
- Phosphorus-arsenic interaction mitigates toxicity and accumulation of arsenic in rice grown in contaminated fields.Plant cell reports · 2026Article
- Impacts of arsenic contamination on plants and the role of microalgae in arsenic stress mitigation for sustainable agriculture.Biodegradation · 2026Review
- Screening of five mulberry (Morus spp.) cultivars for safe utilization of arsenic-contaminated tailings.Scientific reports · 2026Article
- Review
- Mitigating the harmful consequences of arsenic on celosia plants via the use of GABA.BMC plant biology · 2026Article
- Decoding heavy metals (CdScientific reports · 2026Article
- Article
- Arsenic migration and transformation, greenhouse gas dynamics, and their coupled relationships in paddy fields.Frontiers in microbiology · 2026Review
- Mitigation Potential of bio-fabricated selenium nanoparticles on arsenic induced stress in morpho-physiological growth of rice (Oryza sativa L.) seedlings.Scientific reports · 2025Article
- Ferrichrysin siderophore from gangetic Aspergillus japonicus: Isolation, Characterization, and role in sustained arsenic tolerance.World journal of microbiology & biotechnology · 2025Article
- Omics advancements towards exploring arsenic toxicity and tolerance in plants: a review.Planta · 2025Review
- Evaluation of the molecular mechanism underlying proline metabolic and catabolic pathways and some morpho-physiological traits of tobacco (Nicotiana tabacum L.) plants under arsenic stress.BMC plant biology · 2025Article
- Screening-level ecological risk assessment (SLERA) in an abandoned As-Cu mining area (N Spain): implications of phyto-availability and soil properties on vegetation.Environmental geochemistry and health · 2025Article
- Morpho-Physiological Adaptations of Rice Cultivars Under Heavy Metal Stress: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Control strategies for rice "straighthead" through physicochemical and biological methods on arsenic transformation and transportation.Frontiers in plant science · 2025Review
- New nano-ferro-silicon biochar promotes plant growth and grain yield under arsenic stress in rice.Frontiers in plant science · 2025Article
- EvaluatingFrontiers in plant science · 2025Article
104 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The two forms of inorganic arsenic, arsenate (AsV) and arsenite (AsIII), are easily taken up by the cells of the plant root. Once in the cell, AsV can be readily converted to AsIII, the more toxic of the two forms. AsV and AsIII both disrupt plant metabolism, but through distinct mechanisms. AsV is a chemical analog of phosphate that can disrupt at least some phosphate-dependent aspects of metabolism. AsV can be translocated across cellular membranes by phosphate transport proteins, leading to imbalances in phosphate supply. It can compete with phosphate during phosphorylation reactions, leading to the formation of AsV adducts that are often unstable and short-lived. As an example, the formation and rapid autohydrolysis of AsV-ADP sets in place a futile cycle that uncouples photophosphorylation and oxidative phosphorylation, decreasing the ability of cells to produce ATP and carry out normal metabolism. AsIII is a dithiol reactive compound that binds to and potentially inactivates enzymes containing closely spaced cysteine residues or dithiol co-factors. Arsenic exposure generally induces the production of reactive oxygen species that can lead to the production of antioxidant metabolites and numerous enzymes involved in antioxidant defense. Oxidative carbon metabolism, amino acid and protein relationships, and nitrogen and sulfur assimilation pathways are also impacted by As exposure. Readjustment of several metabolic pathways, such as glutathione production, has been shown to lead to increased arsenic tolerance in plants. Species- and cultivar-dependent variation in arsenic sensitivity and the remodeling of metabolite pools that occurs in response to As exposure gives hope that additional metabolic pathways associated with As tolerance will be identified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.