ArticleApplied and environmental microbiology2012
Stability and infectivity of cytolethal distending toxin type V gene-carrying bacteriophages in a water mesocosm and under different inactivation conditions.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Harnessing the Infectivity and Stability of Bacteriophage ΦNF-1 in a Phage-Based Product for Sustainable Nitrification Control.Environmental science & technology · 2026Article
- A Bacteriophage-Loaded Microparticle Laden Topical Gel for the Treatment of Multidrug-Resistant Biofilm-Mediated Burn Wound Infection.AAPS PharmSciTech · 2023Article
- Bacteriophages in sewage: abundance, roles, and applications.FEMS microbes · 2022Article
- Abundance of antibiotic resistance genes in bacteria and bacteriophages isolated from wastewater in Shiraz.Molecular biology research communications · 2021Article
- Review
- Don't Shut the Stable Door after the Phage Has Bolted-The Importance of Bacteriophage Inactivation in Food Environments.Viruses · 2019Review
- Bacteriophage cocktail for biocontrol of Escherichia coli O157:H7: Stability and potential allergenicity study.PloS one · 2018Article
- Review
- UV-Sensitivity of Shiga Toxin-Converting Bacteriophage Virions Φ24B, 933W, P22, P27 and P32.Toxins · 2015Article
- Persistence of infectious Shiga toxin-encoding bacteriophages after disinfection treatments.Applied and environmental microbiology · 2014Article
- Evolution of a self-inducible cytolethal distending toxin type V-encoding bacteriophage from Escherichia coli O157:H7 to Shigella sonnei.Journal of virology · 2013Article
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3 authors.
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Abstract
Two cytolethal distending toxin (Cdt) type V-encoding bacteriophages (Φ62 and Φ125) were induced spontaneously from their wild-type Escherichia coli strains and from the lysogens generated in Shigella sonnei. The stability of Cdt phages was determined at various temperatures and pH values after 1 month of storage by means of infectivity tests using a plaque blot assay and analysis of phage genomes using real-time quantitative PCR (qPCR): both were highly stable. We assessed the inactivation of Cdt phages by thermal treatment, chlorination, UV radiation, and in a mesocosm in both summer and winter. The results for the two Cdt phages showed similar trends and were also similar to the phage SOM23 used for reference, but they showed a much higher persistence than Cdt-producing E. coli. Cdt phages showed maximal inactivation after 1 h at 70°C, 30 min of UV radiation, and 30 min of contact with a 10-ppm chlorine treatment. Inactivation in a mesocosm was higher in summer than in winter, probably because of solar radiation. The treatments reduced the number of infectious phages but did not have a significant effect on the Cdt phage particles detected by qPCR. Cdt phages were quantified by qPCR in 73% of river samples, and these results suggest that Cdt phages are a genetic vehicle and the natural reservoir for cdt in the environment.
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