Evidence map›Paper›PMID 22684937›Full record

ArticleThe Journal of comparative neurology2012

The origin of the Drosophila subretinal pigment layer.

Andrew Tomlinson

Abstract read
In one paragraph

Article in The Journal of comparative neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Cellular innovations and diversity in the lepidopteran compound eye.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  2. Article
  3. Article
  4. Differential regulation of sleep by blue, green, and red light inFrontiers in behavioral neuroscience · 2024
    Article
  5. Article
  6. Article
  7. The Role of microRNAs in theFrontiers in cell and developmental biology · 2022
    Review
  8. Review
  9. Cellular homeostasis in theMolecular biology of the cell · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Andrew TomlinsonDepartment of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. at41@columbia.edu
Columbia University · US

Funding

RETINA--THE CONTROL OF PHOTORECEPTOR CELL FATER01EY012536 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TOMLINSON, ANDREW · 1999 to 2011
$4.1M
NEI NIH HHS R01 EY 012536NEI NIH HHS R01 EY012536
6 · The paper itself

Abstract

Optical insulation plays a critical role in the fine visual acuity of the Drosophila compound eye. Screening pigments expressed by a number of cell types contribute to this phenomenon. They provide optical insulation that prevents extraneous light rays from inappropriately activating the photoreceptors. This optical insulation can be divided into two categories; the insulation of the individual ommatidia, and the insulation of the compound eye as a whole. The whole-eye insulation is provided by two sources. The sides of the eye are optically insulated by the pigment rim, a band of pigment cells that circumscribes the eye. The base of the eye is insulated by the subretinal pigment layer; a thick layer of pigment that lies directly underneath the retina. How this subretinal pigment layer is generated has not been clearly described. Here, experiments that manipulate pigment expression during eye development suggest that the subretinal pigment layer is directly derived from pigment cells in the overlying retina.

Indexed as

AnimalsAnimals, Genetically ModifiedATP-Binding Cassette TransportersDrosophila melanogasterDrosophila ProteinsEye ProteinsPhotoreceptor Cells, InvertebrateRetinal Pigment EpitheliumRetinal PigmentsVisual AcuityATP-Binding Cassette TransportersDrosophila ProteinsEye ProteinsRetinal Pigmentsw protein, Drosophila

Identifiers

PMID22684937
PMCPMC3955728
OpenAlexW1989528165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.