Evidence map›Paper›PMID 22684926›Full record

ArticleInternational journal of hematology2012

Progressive multifocal leukoencephalopathy following treatment with bendamustine and rituximab.

Sean Warsch, Peter J Hosein, Michele I Morris, Uygar Teomete, Ronald Benveniste, Jennifer R Chapman, Izidore S Lossos

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Host-Immune Interactions in JC Virus Reactivation and Development of Progressive Multifocal Leukoencephalopathy (PML).Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2019
    Review
  5. Article
  6. Article
  7. [A rare cause of a progressive speech impairment].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sean WarschDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Peter J Hosein
Michele I Morris
Uygar Teomete
Ronald Benveniste
Jennifer R Chapman
Izidore S Lossos
University of Miami · USSylvester Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 66-year-old female developed progressive multifocal leukoencephalopathy (PML) 17 months after treatment with bendamustine and rituximab chemoimmunotherapy. During her evaluation for PML, she was found to have a CD4 count of 176 cells/μL (reference range 492-1740). The patient demonstrated spontaneous recovery of symptoms that occurred in parallel with recovery of the CD4 counts. While PML is associated with rituximab therapy, the timing and patients' clinical course are atypical, raising the possibility of a previously unreported association with bendamustine therapy.

Indexed as

AgedAntibodies, Monoclonal, Murine-DerivedAntineoplastic Combined Chemotherapy ProtocolsBendamustine HydrochlorideBiopsyBrainFemaleHumansLeukoencephalopathy, Progressive MultifocalLymphoma, Mantle-CellMagnetic Resonance ImagingNitrogen Mustard CompoundsRituximabAntibodies, Monoclonal, Murine-DerivedBendamustine HydrochlorideNitrogen Mustard CompoundsRituximab

Identifiers

PMID22684926
OpenAlexW2015436507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.