Evidence map›Paper›PMID 22684783›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2012

Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for specific cellular imaging.

Jiangbo Yu, Changfeng Wu, Xuanjun Zhang, Fangmao Ye, Maria Elena Gallina, Yu Rong, I-Che Wu, Wei Sun, Yang-Hsiang Chan, Daniel T Chiu

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
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  11. Review
  12. Citrate-Based Fluorescent Biomaterials.Advanced healthcare materials · 2018
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiangbo YuDepartment of Chemistry, University of Washington, Seattle, WA 98195, USA.
Changfeng Wu
Xuanjun Zhang
Fangmao Ye
Maria Elena Gallina
Yu Rong
I-Che Wu
Wei Sun
Yang-Hsiang Chan
Daniel T Chiu

Funding

Single-Molecule Studies of Synaptic VesiclesR01NS062725 · NINDS · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T · 2008 to 2011
$1.3M
High Sensitivity Detection and Isolation of Circulating Tumor CellsR21CA147831 · NCI · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T · 2010 to 2012
$631k
NCI NIH HHS CA147831NCI NIH HHS R21 CA147831NINDS NIH HHS NS062725NINDS NIH HHS R01 NS062725
6 · The paper itself

Abstract

A facile cross-linking strategy covalently links functional molecules to semiconducting polymer dots (Pdots) while simultaneously providing functional groups for biomolecular conjugation. In addition to greatly enhanced stability, the formed Pdots are small (<10 nm), which can be difficult to achieve with current methods but is highly desirable for most biological applications. These characteristics are significant for improving labeling efficiency and sensitivity in cellular assays that employ Pdots.

Indexed as

SemiconductorsAminesCell Line, TumorHumansMaleatesMolecular ImagingPolystyrenesStaining and LabelingAminesMaleatespoly(styrene-alt-maleic anhydride)poly(styrene-co-maleic anhydride)Polystyrenes

Identifiers

PMID22684783
PMCPMC3433747

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.