Evidence map›Paper›PMID 22684777›Full record

ArticleAngewandte Chemie (International ed. in English)2012

DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems.

Shenliang Wang, Jia Guo, Toshikazu Ono, Eric T Kool

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Single-CellFrontiers in cell and developmental biology · 2018
    Article
  6. Luminescent Carbon Dot Mimics Assembled on DNA.Journal of the American Chemical Society · 2017
    Article
  7. Color-Change Photoswitching of an Alkynylpyrene Excimer Dye.Angewandte Chemie (International ed. in English) · 2017
    Article
  8. Article
  9. In Vitro Fluorogenic Real-Time Assay of the Repair of Oxidative DNA Damage.Chembiochem : a European journal of chemical biology · 2015
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shenliang WangDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Jia Guo
Toshikazu Ono
Eric T Kool

Funding

POLYFLUOROPHORES ASSEMBLED ON A DNA SCAFFOLDR01GM067201 · NIGMS · STANFORD UNIVERSITY · PI KOOL, ERIC T. · 2003 to 2011
$2.2M
NIGMS NIH HHS GM067201NIGMS NIH HHS R01 GM067201
6 · The paper itself

Abstract

Dye-ing to live: Spectral limitations of common organic dyes make it difficult or impossible to visualize and follow multiple biological components in rapidly moving systems. The development of a multispectral set of improved DNA-scaffolded fluorophores is described. Their use in multicolor cellular imaging (see scheme) and in tracking of biological motions on the subsecond timescale is demonstrated.

Indexed as

AnimalsDNAFluorescent DyesHeLa CellsHumansMicroscopy, FluorescenceOligonucleotidesParamecium caudatumZebrafishDNAFluorescent DyesOligonucleotides

Identifiers

PMID22684777
PMCPMC3489938

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.